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Gene Expression Data
Assay Details
Assay
Reference: J:160668 Yang H, et al., Gfi1-Cre knock-in mouse line: A tool for inner ear hair cell-specific gene deletion. Genesis. 2010 Apr 13;48(6):400-406
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6725123
Gene symbol: Myo6
Gene name: myosin VI
Antibody: anti-Myo6 (25-6791)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 4a: postnatal day 0; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Myo6; green - Cre reporter
Structure Level Pattern Image Note
TS27: cochlea epithelium Present Regionally restricted 4a' , 4a'' Expression is seen in the inner and outer hair cells.
Specimen 4b: postnatal day 0; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Myo6; green - Cre reporter
Structure Level Pattern Image Note
TS27: saccule epithelium Present Regionally restricted 4b' , 4b'' Expression is seen in hair cells.
Specimen 4c: postnatal day 0; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Myo6; green - Cre reporter
Structure Level Pattern Image Note
TS27: utricle epithelium Present Regionally restricted 4c' , 4c'' Expression is seen in hair cells.
Specimen 4d: postnatal day 0; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Myo6; green - Cre reporter
Structure Level Pattern Image Note
TS27: crista ampullaris Present Regionally restricted 4d' , 4d'' Expression is seen in hair cells.
Specimen 4e: postnatal day 7; Gfi1tm1(cre)Gan/Gfi1+, Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Double labeled: red - Myo6; green - Cre reporter
Structure Level Pattern Image Note
TS28: cochlea epithelium Present Regionally restricted 4e' , 4e'' Expression is seen in the inner and outer hair cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory