Results
|
Specimen
1a:
embryonic day 13.5; Hoxa11tm1Dmwe/Hoxa11 +
(more )
Note: Double labeled: green - Hoxa11 reporter; red - Sox9 (assay MGI:6724561).
Specimen
1a:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Hoxa11tm1Dmwe/Hoxa11+
|
Age:
|
embryonic day 13.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Hoxa11 reporter; red - Sox9 (assay MGI:6724561).
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: forearm rest of mesenchyme |
Present |
Regionally restricted |
1a inset
,
1a
|
Expression is seen in cells of the perichondrium surrounding the radius/ulna chondrocyte anlage.
|
TS21: perichondrium |
Present |
Regionally restricted |
1a inset
,
1a
|
Expression is seen in cells of the perichondrium surrounding the radius/ulna chondrocyte anlage.
|
Specimen
1b:
embryonic day 14.5; Hoxa11tm1Dmwe/Hoxa11 +
(more )
Note: Double labeled: green - Hoxa11 reporter; magenta - Sp7 (assay MGI:6724558).
Specimen
1b:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Hoxa11tm1Dmwe/Hoxa11+
|
Age:
|
embryonic day 14.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Hoxa11 reporter; magenta - Sp7 (assay MGI:6724558).
|
Structure |
Level |
Pattern |
Image |
Note |
TS22: periosteum |
Present |
Regionally restricted |
1b inset
,
1b
|
Expression is seen in the outer periosteum, immediately adjacent to the differentiating osteoblast layer.
|
TS22: radius cartilage condensation |
Present |
Regionally restricted |
1b inset
,
1b
|
Expression is seen in the outer periosteum, immediately adjacent to the differentiating osteoblast layer.
|
TS22: ulna cartilage condensation |
Present |
Regionally restricted |
1b inset
,
1b
|
Expression is seen in the outer periosteum, immediately adjacent to the differentiating osteoblast layer.
|
Specimen
1c:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Hoxa11tm1Dmwe/Hoxa11+
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: periosteum |
Present |
Regionally restricted |
1c
|
Expression is seen in the perichondrium as well as on endosteal bone surfaces.
|
TS26: radius |
Present |
Regionally restricted |
1c
|
Expression is seen in the perichondrium as well as on endosteal bone surfaces.
|
TS26: ulna |
Present |
Regionally restricted |
1c
|
Expression is seen in the perichondrium as well as on endosteal bone surfaces.
|
Specimen
1d:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Hoxa11tm1Dmwe/Hoxa11+
|
Age:
|
postnatal week 2
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: radius |
Present |
Regionally restricted |
1d
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
TS28: periosteum |
Present |
Regionally restricted |
1d
,
1d inset
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
TS28: ulna |
Present |
Regionally restricted |
1d
,
1d inset
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
TS28: bone marrow |
Present |
Regionally restricted |
1d inset
,
1d
|
Expression is seen in stromal cells within the bone marrow space.
|
Specimen
1e:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Hoxa11tm1Dmwe/Hoxa11+
|
Age:
|
postnatal week 8
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: radius |
Present |
Regionally restricted |
1e
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
TS28: periosteum |
Present |
Regionally restricted |
1e inset
,
1e
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
TS28: ulna |
Present |
Regionally restricted |
1e inset
,
1e
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
TS28: bone marrow |
Present |
Regionally restricted |
1e
,
1e inset
|
Expression is seen in stromal cells within the bone marrow space.
|
Specimen
1f:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Hoxa11tm1Dmwe/Hoxa11+
|
Age:
|
postnatal month 10
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: radius |
Present |
Regionally restricted |
1f
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
TS28: periosteum |
Present |
Regionally restricted |
1f
,
1f inset
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
TS28: ulna |
Present |
Regionally restricted |
1f
,
1f inset
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
TS28: bone marrow |
Present |
Regionally restricted |
1f
,
1f inset
|
Expression is seen in stromal cells within the bone marrow space.
|
Specimen
1g:
postnatal week 8; Hoxa11tm1Dmwe/Hoxa11 +
(more )
Note: Double labeled: green - Hoxa11 reporter; red - Sp7 (assay MGI:6724558).
Specimen
1g:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Hoxa11tm1Dmwe/Hoxa11+
|
Age:
|
postnatal week 8
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Hoxa11 reporter; red - Sp7 (assay MGI:6724558).
|
Specimen
1h - E15.5:
embryonic day 15.5; Hoxa11tm1Dmwe/Hoxa11 +
(more )
Specimen
1h - E15.5:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Hoxa11tm1Dmwe/Hoxa11+
|
Age:
|
embryonic day 15.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
1h - 8 weeks:
postnatal week 8; Hoxa11tm1Dmwe/Hoxa11 +
(more )
Specimen
1h - 8 weeks:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Hoxa11tm1Dmwe/Hoxa11+
|
Age:
|
postnatal week 8
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
1h - P4:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Hoxa11tm1Dmwe/Hoxa11+
|
Age:
|
postnatal day 4
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Specimen
1i:
postnatal week 2; Hoxa11tm1Dmwe/Hoxa11 +
(more )
Note: Double labeled: green - Hoxa11 reporter; red - Postn (assay MGI:6724559).
Specimen
1i:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Hoxa11tm1Dmwe/Hoxa11+
|
Age:
|
postnatal week 2
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Hoxa11 reporter; red - Postn (assay MGI:6724559).
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: periosteum |
Present |
Non-Uniform |
1i green
,
1i merge
|
The expression is seen in the outer and inner periosteum; it is weaker in the inner periosteal layer.
|
Specimen
1j:
postnatal week 8; Hoxa11tm1Dmwe/Hoxa11 +
(more )
Note: Double labeled: green - Hoxa11 reporter; red - Postn (assay MGI:6724559).
Specimen
1j:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
|
Mutant Allele(s):
|
Hoxa11tm1Dmwe/Hoxa11+
|
Age:
|
postnatal week 8
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Double labeled: green - Hoxa11 reporter; red - Postn (assay MGI:6724559).
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: periosteum |
Present |
Non-Uniform |
1j green
,
1j merge
|
The expression is seen in the outer and inner periosteum; it is weaker in the inner periosteal layer.
|
Specimen
7a:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * C57BL/6NCrl
|
Mutant Allele(s):
|
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Hoxa11tm1Dmwe/Hoxa11+ Leprtm2(cre)Rck/Lepr+
|
Age:
|
embryonic day 18.5
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Conditional mutant. Double labeled: green - Hoxa11 reporter; red - Cre reporter.
|
Structure |
Level |
Pattern |
Image |
Note |
TS26: forelimb bone |
Present |
Regionally restricted |
7a
|
Expression is seen through the periosteum and along bone surfaces of the primary spongiosa.
|
TS26: periosteum |
Present |
Regionally restricted |
7a
|
Expression is seen through the periosteum and along bone surfaces of the primary spongiosa.
|
Specimen
7b:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * C57BL/6NCrl
|
Mutant Allele(s):
|
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Hoxa11tm1Dmwe/Hoxa11+ Leprtm2(cre)Rck/Lepr+
|
Age:
|
postnatal week 2
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Conditional mutant. Double labeled: green - Hoxa11 reporter; red - Cre reporter.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: bone marrow |
Present |
Single cells |
7b
|
Expression is seen in stromal cells in the bone marrow space.
|
TS28: ulna |
Present |
Single cells |
7b
|
Expression is seen in stromal cells in the bone marrow space.
|
Specimen
7b':
(close )
Genetic Background:
|
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * C57BL/6NCrl
|
Mutant Allele(s):
|
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Hoxa11tm1Dmwe/Hoxa11+ Leprtm2(cre)Rck/Lepr+
|
Age:
|
postnatal week 2
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Conditional mutant. Double labeled: green - Hoxa11 reporter; red - Cre reporter.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: periosteum |
Present |
Regionally restricted |
7b'
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
TS28: ulna |
Present |
Regionally restricted |
7b'
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
Specimen
7c:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * C57BL/6NCrl
|
Mutant Allele(s):
|
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Hoxa11tm1Dmwe/Hoxa11+ Leprtm2(cre)Rck/Lepr+
|
Age:
|
postnatal week 4
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Conditional mutant. Double labeled: green - Hoxa11 reporter; red - Cre reporter.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: bone marrow |
Present |
Single cells |
7c
|
Expression is seen in stromal cells in the bone marrow space.
|
TS28: ulna |
Present |
Single cells |
7c
|
Expression is seen in stromal cells in the bone marrow space.
|
Specimen
7c':
(close )
Genetic Background:
|
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * C57BL/6NCrl
|
Mutant Allele(s):
|
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Hoxa11tm1Dmwe/Hoxa11+ Leprtm2(cre)Rck/Lepr+
|
Age:
|
postnatal week 4
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Conditional mutant. Double labeled: green - Hoxa11 reporter; red - Cre reporter.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: periosteum |
Present |
Regionally restricted |
7c'
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
TS28: ulna |
Present |
Regionally restricted |
7c'
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
Specimen
7d:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * C57BL/6NCrl
|
Mutant Allele(s):
|
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Hoxa11tm1Dmwe/Hoxa11+ Leprtm2(cre)Rck/Lepr+
|
Age:
|
postnatal week 8
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Conditional mutant. Double labeled: green - Hoxa11 reporter; red - Cre reporter.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: bone marrow |
Present |
Single cells |
7d
|
Expression is seen in stromal cells in the bone marrow space.
|
TS28: periosteum |
Present |
Single cells |
7d
|
Expression is seen in stromal cells in the bone marrow space.
|
Specimen
7d':
(close )
Genetic Background:
|
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * C57BL/6NCrl
|
Mutant Allele(s):
|
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Hoxa11tm1Dmwe/Hoxa11+ Leprtm2(cre)Rck/Lepr+
|
Age:
|
postnatal week 8
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Conditional mutant. Double labeled: green - Hoxa11 reporter; red - Cre reporter.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: periosteum |
Present |
Regionally restricted |
7d'
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
TS28: ulna |
Present |
Regionally restricted |
7d'
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
Specimen
7e:
(close )
Genetic Background:
|
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * C57BL/6NCrl
|
Mutant Allele(s):
|
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Hoxa11tm1Dmwe/Hoxa11+ Leprtm2(cre)Rck/Lepr+
|
Age:
|
postnatal week 15
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Conditional mutant. Double labeled: green - Hoxa11 reporter; red - Cre reporter.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: bone marrow |
Present |
Single cells |
7e
|
Expression is seen in stromal cells in the bone marrow space.
|
TS28: ulna |
Present |
Single cells |
7e
|
Expression is seen in stromal cells in the bone marrow space.
|
Specimen
7e':
(close )
Genetic Background:
|
involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * C57BL/6NCrl
|
Mutant Allele(s):
|
Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ Hoxa11tm1Dmwe/Hoxa11+ Leprtm2(cre)Rck/Lepr+
|
Age:
|
postnatal week 15
|
Sex:
|
Not Specified
|
Type:
|
section
|
Fixation:
|
4% Paraformaldehyde
|
Embedding:
|
Cryosection
|
Note:
|
Conditional mutant. Double labeled: green - Hoxa11 reporter; red - Cre reporter.
|
Structure |
Level |
Pattern |
Image |
Note |
TS28: periosteum |
Present |
Regionally restricted |
7e'
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
TS28: ulna |
Present |
Regionally restricted |
7e'
|
Expression is seen on the periosteal surface as well as on endosteal bone surfaces.
|
|