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Cdkn2aem3(cre/ERT2)Smoc
Endonuclease-mediated Allele Detail
Summary
Symbol: Cdkn2aem3(cre/ERT2)Smoc
Name: cyclin dependent kinase inhibitor 2A; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
MGI ID: MGI:6724360
Synonyms: Cdkn2aem(Luc-tdTomato-CreERT2)Smoc, Cdkn2a-Luc-2A-tdTomato-2A-CreERT2
Gene: Cdkn2a  Location: Chr4:89192710-89212856 bp, - strand  Genetic Position: Chr4, 42.15 cM, cytoband C3-C6
Alliance: Cdkn2aem3(cre/ERT2)Smoc page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Cdkn2aem3(cre/ERT2)Smoc expression driven by 1 gene
 
Mutation detailsA Luc-2A-tdTomato-2A-CreERT2-WPRE-pA cassette was fused in-frame with exon2 of Cdkn2a-201 transcript such that the exogenous proteins would be translated followed by the first 62aa of Cdkn2a. (J:238766)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cdkn2a (mouse)
Summary of all recombinase alleles driven by Cdkn2a.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdkn2a Mutation:  62 strains or lines available
References
Original:  J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory