Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Hopxem1(dre/ERT2)Smoc
Name:	HOP homeobox; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
MGI ID:	MGI:6724252
Synonyms:	Hopx-2A-DreER, Hopxem1(2A-DreERT2)Smoc
Gene:	Hopx  Location: Chr5:77234835-77262968 bp, - strand  Genetic Position: Chr5, 41.45 cM
Alliance:	Hopxem1(dre/ERT2)Smoc page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Hopxem1(dre/ERT2)Smoc expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Hopx (MGI:1916782)   Mutation details: A 2A-DreERT2 expression cassette was knocked into the Hopx gene stop codon site via CRISPR/Cas mediated recombination. (J:238766, J:304636)

Activity:	Tissue activity of this recombinase allele
Driver:	Hopx (mouse) Summary of all recombinase alleles driven by Hopx. Alliance mouse Hopx gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hopx Mutation:	11 strains or lines available

Original:	J:304636 Han X, et al., A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. Cell Stem Cell. 2021 Feb 2;
All:	2 reference(s)