Flt3em2(dre/ERT2)Smoc
Endonuclease-mediated Allele Detail
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Symbol: |
Flt3em2(dre/ERT2)Smoc |
Name: |
FMS-like tyrosine kinase 3; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
MGI ID: |
MGI:6724245 |
Synonyms: |
Flt3-2A-DreER, Flt3em2(2A-DreERT2)Smoc |
Gene: |
Flt3 Location: Chr5:147267551-147337299 bp, - strand Genetic Position: Chr5, 86.88 cM, cytoband G3
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Alliance: |
Flt3em2(dre/ERT2)Smoc page
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Allele Type: |
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Endonuclease-mediated (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Flt3em2(dre/ERT2)Smoc expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Flt3 (MGI:95559) |
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Mutation details: A 2A-DreERT2 expression cassette was knocked into the Flt3 gene stop codon site via CRISPR/Cas mediated recombination.
(J:238766, J:304636)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Flt3
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Flt3 Mutation: |
83 strains or lines available
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Original: |
J:304636 Han X, et al., A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. Cell Stem Cell. 2021 Feb 2; |
All: |
2 reference(s) |
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