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Gene Expression Data
Assay Details
Assay
Reference: J:193413 Bildsoe H, et al., The mesenchymal architecture of the cranial mesoderm of mouse embryos is disrupted by the loss of Twist1 function. Dev Biol. 2013 Feb 15;374(2):295-307
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6724076
Gene symbol: Twist1
Gene name: twist basic helix-loop-helix transcription factor 1
Antibody: anti-Twist1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1F: embryonic day 8.0 (more )
Note: two-somite stage
Structure Level Pattern Image Note
TS12: head mesenchyme Present Regionally restricted 1F Expressed in the cranial mesoderm.
Specimen 1G: embryonic day 8.5; Mesp1tm2(cre)Ysa/Mesp1+, Twist1+/Twist1tm2Bhr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS13: head mesenchyme Present Regionally restricted 1G Expressed in the cranial mesoderm.
Specimen 1H: embryonic day 8.5; Mesp1tm2(cre)Ysa/Mesp1+, Twist1tm1Bhr/Twist1tm2Bhr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS13: head mesenchyme Ambiguous Regionally restricted 1H No expression in the cranial mesoderm.
Specimen S3B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: vault of skull Present S3B
TS21: chondrocranium Absent S3B hypochiasmatic cartilage
Specimen S3D: embryonic day 13.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: vault of skull Present S3D
Specimen S3E: embryonic day 13.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: vault of skull Present S3E
TS21: chondrocranium Absent S3E hypochiasmatic cartilage
Specimen S3G/H: embryonic day 13.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Mesp1tm2(cre)Ysa/Mesp1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: extrinsic ocular pre-muscle mass Absent S3H , S3G
TS21: upper eyelid Present S3G
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory