Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Foxa2/Sox9-cre,-lacZ)#Vleu
Name:	transgene insertion, Victor Leung
MGI ID:	MGI:6724034
Synonyms:	Foxa2mNE-Cre, Tg(Rr241/Sox9-cre,-lacZ)#Vleu
Transgene:	Tg(Foxa2/Sox9-cre,-lacZ)#Vleu  Location: unknown
Alliance:	Tg(Foxa2/Sox9-cre,-lacZ)#Vleu page

Strain of Origin:

(C57BL/6 x CBA)F1

Transgene Type:    Transgenic (Recombinase, Reporter) Mutation:    Insertion   Tg(Foxa2/Sox9-cre,-lacZ)#Vleu expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Foxa2 (MGI:1347476)   Mutation details: This transgene contains the 520bp minimal notochord enhancer (Rr241) of the mouse Foxa2 gene fused to the upstream genomic sequence of the Sox9 gene followed by replacing the coding region of Sox9 with the Cre recombinase gene and an IRES-lacZ reporter inserted between the Cre Stop codon and the Sox9 polyadenylation sequence. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:301098)

Activity:	Tissue activity of this recombinase allele
Driver:	Foxa2 (mouse) Summary of all recombinase alleles driven by Foxa2. Comparative matrix view of recombinase activities Alliance mouse Foxa2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:301098 Au TYK, et al., Transformation of resident notochord-descendent nucleus pulposus cells in mouse injury-induced fibrotic intervertebral discs. Aging Cell. 2020 Nov;19(11):e13254
All:	3 reference(s)