About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:193413 Bildsoe H, et al., The mesenchymal architecture of the cranial mesoderm of mouse embryos is disrupted by the loss of Twist1 function. Dev Biol. 2013 Feb 15;374(2):295-307
Assay type: RNA in situ
MGI Accession ID: MGI:6723947
Gene symbol: Twist1
Gene name: twist basic helix-loop-helix transcription factor 1
Probe: Twist1 probe5
Probe preparation: Antisense RNA
Results
Specimen 1C: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo mesoderm Present Regionally restricted 1C Expressed in the anterior-most mesoderm population underlying the anterior ectoderm but absent from the nascent mesoderm.
TS11: primitive streak Absent 1C
Specimen 1D/E: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: embryo mesoderm Present Regionally restricted 1E , 1D Expressed in the mesoderm beneath the cephalic neural folds.
Specimen 1I: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: head mesenchyme Present 1I Expressed in the cranial mesenchyme and frontonasal tissues.
TS15: 1st branchial arch Present 1I
TS15: 2nd branchial arch Present 1I
Specimen 1Ii/K: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: head mesenchyme Present 1K , 1Ii Expressed in the cranial mesenchyme.
TS15: 1st branchial arch Present 1Ii
Specimen 1J: embryonic day 9.5; Mesp1tm2(cre)Ysa/Mesp1+, Twist1tm1Bhr/Twist1tm2Bhr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: head mesenchyme Present Regionally restricted 1J No expression in the cranial mesenchyme. Expressed in the frontonasal tissues.
TS15: 1st branchial arch Present 1J
TS15: 2nd branchial arch Present 1J
Specimen 1Ji/L: embryonic day 9.5; Mesp1tm2(cre)Ysa/Mesp1+, Twist1tm1Bhr/Twist1tm2Bhr (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: head mesenchyme Present Regionally restricted 1Ji , 1L No expression in the cranial mesenchyme.
TS15: 1st branchial arch Present 1Ji , 1L
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory