Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Tbx21-cre)1Yyos
Name:	transgene insertion 1, Yoshihiro Yoshihara
MGI ID:	MGI:6721441
Synonyms:	Cla-Cre
Transgene:	Tg(Tbx21-cre)1Yyos  Location: unknown
Alliance:	Tg(Tbx21-cre)1Yyos page

Strain of Origin:

B6D2F1

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Tbx21-cre)1Yyos expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Tbx21 (MGI:1888984)   Mutation details: The transgene consisting of the 5.0-kb upstream enhancer/promoter region sequence of the mouse Tbx21 gene was fused to the bacteriophage P1 Cre recombinase gene with the human -globin gene intron and simian virus 40 polyadenylation signal driving cre expression specifically in the mitral/tufted cells of the olfactory bulb. The DNA construct was purified and initialized then injected into the pronucleus of fertilized eggs that were obtained from crossing C57BL/6J and DBA/2J mice. Seven transgenic mouse lines were established and one (line no. 1) showed ectopic expression of Cre protein specifically in the claustrum and was used for the study. (J:293062)

Activity:	Tissue activity of this recombinase allele
Driver:	Tbx21 (mouse) Summary of all recombinase alleles driven by Tbx21. Comparative matrix view of recombinase activities Alliance mouse Tbx21 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:293062 Narikiyo K, et al., The claustrum coordinates cortical slow-wave activity. Nat Neurosci. 2020 Jun;23(6):741-753
All:	1 reference(s)