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Tg(Pvalb-GFP)IITkane
Transgene Detail
Summary
Symbol: Tg(Pvalb-GFP)IITkane
Name: transgene insertion II, Takeshi Kaneko
MGI ID: MGI:6721439
Synonyms: PV/myrGFP-
Transgene: Tg(Pvalb-GFP)IITkane  Location: unknown  
Alliance: Tg(Pvalb-GFP)IITkane page
Transgene
origin
Strain of Origin:  B6D2F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe transgene consists of a myristoylation/palmitoylation site-attached GFP (myrGFP) inserted into the start codon located in the exon 2 of the Pvalb gene so that it is under the control of the mouse Pvalb promoter. The modified BAC transgene construct DNA was purified and linearized then injected into pronuclei of B6D2F1 mouse zygotes. Three founder lines I, II, III were generated. Line II was used for the study. (J:187049)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:187049 Kameda H, et al., Parvalbumin-producing cortical interneurons receive inhibitory inputs on proximal portions and cortical excitatory inputs on distal dendrites. Eur J Neurosci. 2012 Mar;35(6):838-54
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory