Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Col1a2em1(cre/ERT2)Bzsh
Name:	collagen, type I, alpha 2; endonuclease-mediated mutation 1, Bin Zhou
MGI ID:	MGI:6721050
Synonyms:	Col1a2-2A-CreER
Gene:	Col1a2  Location: Chr6:4505618-4541543 bp, + strand  Genetic Position: Chr6, 1.81 cM
Alliance:	Col1a2em1(cre/ERT2)Bzsh page

Strain of Origin:

Not Specified

Allele Type:    Endonuclease-mediated (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Col1a2em1(cre/ERT2)Bzsh expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Col1a2 (MGI:88468)   Mutation details: Using the CRISPR/Cas9 technology, the line was generated by inserting a cDNA encoding cre/ERT2 recombinase into the translational stop codon of the Col1a2 gene, following endogenous Col1a2 by the self-cleaving peptide 2A sequence. (J:248362)

Activity:	Tissue activity of this recombinase allele
Driver:	Col1a2 (mouse) Summary of all recombinase alleles driven by Col1a2. Comparative matrix view of recombinase activities Alliance mouse Col1a2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Col1a2 Mutation:	119 strains or lines available

Original:	J:248362 He L, et al., Preexisting endothelial cells mediate cardiac neovascularization after injury. J Clin Invest. 2017 Aug 01;127(8):2968-2981
All:	3 reference(s)