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Gene Expression Data
Assay Details
Assay
Reference: J:185565 Wessels A, et al., Epicardially derived fibroblasts preferentially contribute to the parietal leaflets of the atrioventricular valves in the murine heart. Dev Biol. 2012 Jun 15;366(2):111-24
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6720869
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Antibody: anti-Sox-9 (H-90; sc-20095)
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 7A: embryonic day 13.0; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Wt1-cre)#Jbeb/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: atrioventricular sulcus Present 7A
TS21: mitral valve Present 7A
Specimen 7B: embryonic day 13.0; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Wt1-cre)#Jbeb/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: atrioventricular sulcus Present 7B
TS21: mitral valve Present 7B
Specimen 7C: embryonic day 13.0; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Wt1-cre)#Jbeb/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: atrioventricular sulcus Present 7C
TS21: mitral valve Present 7C
Specimen 7D: embryonic day 17.0; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Wt1-cre)#Jbeb/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: atrioventricular sulcus Present 7D
TS25: visceral pericardium Trace 7D Very low expression.
TS25: mitral valve leaflet Present 7D No difference was observed betweenthe levels of expression in the epicardially derived mesenchyme and the endocardially derived mesenchyme.
Specimen 7E: embryonic day 17.0; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Wt1-cre)#Jbeb/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: atrioventricular sulcus Present 7E
TS25: mitral valve leaflet Present 7E
Specimen 7F: embryonic day 17.0; Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+, Tg(Wt1-cre)#Jbeb/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: atrioventricular sulcus Present 7F
TS25: mitral valve leaflet Present 7F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory