Fezf2tm1.1(cre/ERT2)Zjh
Targeted Allele Detail
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Symbol: |
Fezf2tm1.1(cre/ERT2)Zjh |
Name: |
Fez family zinc finger 2; targeted mutation 1.1, Z Josh Huang |
MGI ID: |
MGI:6720836 |
Synonyms: |
Fezf2-2A-CreER, Fezf2-CreER |
Gene: |
Fezf2 Location: Chr14:10121574-10127669 bp, + strand Genetic Position: Chr14, 6.36 cM
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Alliance: |
Fezf2tm1.1(cre/ERT2)Zjh page
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Allele Type: |
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Targeted (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Fezf2tm1.1(cre/ERT2)Zjh expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The allele was generated by inserting a 2A-CreER expression cassette in-frame before the STOP codon of the Fezf2 gene. The targeting vectors generated using BAC clones from the RPCI-23&24 library were electroporated into a 129SVj/B6 hybrid ES cell line (v6.5). The Resulting ES cell clones were used for tetraploid complementation to obtain male heterozygous mice. The neo selection cassette was excised by crossing to FlpE strain mice.
(J:323579, J:323692)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Fezf2
(mouse)
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Original: |
J:323692 Matho KS, et al., Genetic dissection of the glutamatergic neuron system in cerebral cortex. Nature. 2021 Oct;598(7879):182-187 |
All: |
8 reference(s) |
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