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Tg(Anks1-GFP,-Anks1*)#Sopa
Transgene Detail
Summary
Symbol: Tg(Anks1-GFP,-Anks1*)#Sopa
Name: transgene insertion, Soochul Park
MGI ID: MGI:6720246
Transgene: Tg(Anks1-GFP,-Anks1*)#Sopa  Location: unknown  
Alliance: Tg(Anks1-GFP,-Anks1*)#Sopa page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Mutation detailsUsing a bacterial artificial chromosome (BAC: RP24-258K7) homologous recombination, a transgene with floxed green fluorescent protein (GFP)-STOP cassette followed by phosphotyrosine binding domain (PTB) deleted Anks1 cDNA (Anks1-dPTB) and the frt-Kana-frt cassette inserted at the mouse Anks1 translation start site was generated. The mutant (Anks1-dPTB) is expressed upon crossing of mice with cre expressing mice to delete floxed GFP cassette. The recombinant BAC transgene was then injected into fertilized C57BL/6 mouse eggs. Three lines were generated with similar expression patterns. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:226953)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:226953 Park S, et al., In Vivo Expression of the PTB-deleted Odin Mutant Results in Hydrocephalus. Mol Cells. 2015 May;38(5):426-31
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory