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Gene Expression Data
Assay Details
Assay
Reference: J:199203 Wu HH, et al., Prenatal expression of MET receptor tyrosine kinase in the fetal mouse dorsal raphe nuclei and the visceral motor/sensory brainstem. Dev Neurosci. 2013;35(1):1-16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6719306
Gene symbol: Met
Gene name: met proto-oncogene
Antibody: anti-MET
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to DyLight 549
Results
Specimen 4b: embryonic day 16.0 (more )
Note: Double labeled with 5-HT Serotonin (green).
Structure Level Pattern Image Note
TS24: midbrain tegmentum Present Regionally restricted 4b , 4c Expression is in the caudal dorsal raphe serotonergic neurons as paired nuclei situated just below the aqueduct.

Specimen 4e: embryonic day 16.0 (more )
Note: Double labeled with 5-HT Serotonin (green).
Structure Level Pattern Image Note
TS24: midbrain tegmentum Present Regionally restricted 4f , 4e Expression is in the caudal dorsal raphe serotonergic neurons as paired nuclei situated just below the aqueduct.

Specimen 4h: embryonic day 16.0 (more )
Note: Double labeled with 5-HT Serotonin (green).
Structure Level Pattern Image Note
TS24: midbrain tegmentum Present Regionally restricted 4i , 4h Expression is in the caudal dorsal raphe serotonergic neurons as paired nuclei situated just below the aqueduct.

Specimen 4j: embryonic day 16.0 (more )
Note: Double labeled with 5-HT Serotonin (green).
Structure Level Pattern Image Note
TS24: midbrain tegmentum Present Regionally restricted 4j Expression is in the caudal dorsal raphe serotonergic neurons as paired nuclei situated just below the aqueduct.

Specimen 4k: embryonic day 18.0 (more )
Note: Double labeled with 5-HT Serotonin (green).
Structure Level Pattern Image Note
TS26: midbrain tegmentum Present Regionally restricted 4k Expression is in the caudal dorsal raphe serotonergic neurons as paired nuclei situated just below the aqueduct.

Specimen 4l: postnatal day 4 (more )
Note: Double labeled with 5-HT Serotonin (green).
Structure Level Pattern Image Note
TS28: dorsal raphe nucleus Present Regionally restricted 4l Expression is in the caudal dorsal raphe serotonergic neurons as paired nuclei situated just below the aqueduct.

Specimen 4m: embryonic day 15.0 (more )
Note: Double labeled with 5-HT Serotonin (green).
Structure Level Pattern Image Note
TS23: midbrain tegmentum Present Regionally restricted 4m Expression is in the caudal dorsal raphe serotonergic neurons as paired nuclei situated just below the aqueduct.

Specimen 4n: embryonic day 15.0; Fevtm1Esd/Fevtm1Esd (more )
Note: Double labeled with 5-HT Serotonin (green).
Structure Level Pattern Image Note
TS23: midbrain tegmentum Absent 4n

Specimen 5a: embryonic day 16.0 (more )
Note: Double labeled: red - Met; green - Th (assay MGI:6719307).
Structure Level Pattern Image Note
TS24: brainstem nucleus Present Regionally restricted 5c , 5a , 5b Expression is in Barrington's nucleus and is absent at the level of the locus coeruleus.

Specimen 5e: embryonic day 16.0 (more )
Note: Double labeled: red - Met; green - Crh (assay MGI:6719308).
Structure Level Pattern Image Note
TS24: brainstem nucleus Present Regionally restricted 5e , 5f Expression is in Barrington's nucleus and is absent at the level of the locus coeruleus.

Specimen S4a: embryonic day 13.0 (more )
Note: Double labeled: red - Met; green - Pax2 (assay MGI:6725105).
Structure Level Pattern Image Note
TS21: brainstem Present Regionally restricted S4a Expression is in subsets of cranial motor nuclei: in and lateral to the dorsal motor nucleus of the tenth nerve.
TS21: brainstem nucleus Present Regionally restricted S4a Expression is in subsets of cranial motor nuclei: in and lateral to the dorsal motor nucleus of the tenth nerve.
TS21: medulla oblongata Present Regionally restricted S4a Expression is in subsets of cranial motor nuclei: in and lateral to the dorsal motor nucleus of the tenth nerve.

Specimen S4b: embryonic day 13.0 (more )
Note: Double labeled: red - Met; green - Pax2 (assay MGI:6725105).
Structure Level Pattern Image Note
TS21: brainstem Present Regionally restricted S4b MET/Pax2 , S4b MET Expression is in subsets of cranial motor nuclei: in and lateral to the dorsal motor nucleus of the tenth nerve.
TS21: brainstem nucleus Present Regionally restricted S4b MET/Pax2 , S4b MET Expression is in subsets of cranial motor nuclei: in and lateral to the dorsal motor nucleus of the tenth nerve.
TS21: medulla oblongata Present Regionally restricted S4b MET/Pax2 , S4b MET Expression is in subsets of cranial motor nuclei: in and lateral to the dorsal motor nucleus of the tenth nerve.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory