Tg(CAG-Eif2s1,-EGFP)11Rjk
Transgene Detail
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| Symbol: |
Tg(CAG-Eif2s1,-EGFP)11Rjk |
| Name: |
transgene insertion 11, Randal J Kaufman |
| MGI ID: |
MGI:6719085 |
| Synonyms: |
eIF2alpha fTg |
| Transgene: |
Tg(CAG-Eif2s1,-EGFP)11Rjk Location: unknown
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| Alliance: |
Tg(CAG-Eif2s1,-EGFP)11Rjk page
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| Strain of Origin: |
C57BL/6J x SJL
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| Transgene Type: |
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Transgenic (Inserted expressed sequence, Reporter) |
| Mutation: |
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Insertion
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Mutation details: This transgene construct contains the following elements: the CAG promoter, a loxP site, the mouse eukaryotic translation initiation factor 2 subunit 1 alpha cDNA, a second loxP site, the EGFP fluorescent marker gene, and bovine globin poly(A) signal sequences. Founder 11 has a single copy of the transgene. The transgene will express Eif2s1 as is, but EGFP after cre-mediated excision of the Eif2s1 sequence.
(J:151620)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:151620 Back SH, et al., Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells. Cell Metab. 2009 Jul;10(1):13-26 |
| All: |
7 reference(s) |
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Analysis Tools
