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Gene Expression Data
Assay Details
Assay
Reference: J:290862 Fulmer D, et al., Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actin. Dev Biol. 2020 Jul 1;463(1):26-38
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6718609
Gene symbol: Col1a1
Gene name: collagen, type I, alpha 1
Antibody: anti-collagen I alpha 1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S13 WT: postnatal day 0 (more )
Note: Double labeled: green - Col1a1; red - Acta2 (assay MGI:6718503).
Structure Level Pattern Image Note
TS27: mitral valve Present S13_upper right , S13_upper left Expression did not completely overlap with Acta2. Acta2 appeared to largely be excluded from Col1a1 expressing cells.
Specimen S13 Het: postnatal day 0; Dhhtm1Ics/Dhh+, Nfatc1tm1.1(cre)Bz/Nfatc1+ (more )
Note: Conditional mutant. Double labeled: green - Col1a1; red - Acta2 (assay MGI:6718503).
Structure Level Pattern Image Note
TS27: mitral valve Present S13_middle left , S13_middle right Expressed in a reciprocal pattern with Acta2 compared to controls.
Specimen S13 cKO: postnatal day 0; Dhhtm1Ics/Dhhtm1Ics, Nfatc1tm1.1(cre)Bz/Nfatc1+ (more )
Note: Conditional mutant. Double labeled: green - Col1a1; red - Acta2 (assay MGI:6718503).
Structure Level Pattern Image Note
TS27: mitral valve Present S13_lower left , S13_lower right Expressed in a reciprocal pattern with Acta2 compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory