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Tg(IgkKL25,-Thy1/Pdgfrb)#Pdg
Transgene Detail
Summary
Symbol: Tg(IgkKL25,-Thy1/Pdgfrb)#Pdg
Name: transgene insertion, Philip D Greenberg
MGI ID: MGI:6718534
Transgene: Tg(IgkKL25,-Thy1/Pdgfrb)#Pdg  Location: unknown  
Alliance: Tg(IgkKL25,-Thy1/Pdgfrb)#Pdg page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThis transgene contains the following elements: the immunoglobulin kappa (Igk) chain promoter, rearranged Igk-V and -J segments, including leader and intron, from the KL25 hybridoma against the lymphocytic choriomeningitis virus (LCMV) WE strain, the Igkc light chain kappa constant domain segment, IRES sequence, a Thy1/Pdgfrb fusion gene (ectodomain of the Thy1 marker gene fused to the transmembrane domain of the mouse Pdgf receptor), and an Igk enhancer element. (J:306923)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:306923 Sammicheli S, et al., Inflammatory monocytes hinder antiviral B cell responses. Sci Immunol. 2016 Oct 21;1(4)
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory