Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Oxtrtm3.1(Oxtr*,cre)Knis
Name:	oxytocin receptor; targeted mutation 1, Katsuhiko Nishimori
MGI ID:	MGI:6718390
Synonyms:	Oxtr cDNAHA-Ires-Cre
Gene:	Oxtr  Location: Chr6:112450644-112466904 bp, - strand  Genetic Position: Chr6, 52.27 cM, cytoband E3
Alliance:	Oxtrtm3.1(Oxtr*,cre)Knis page

Germline Transmission:	Earliest citation of germline transmission: J:287190
Parent Cell Line:	E14TG2a (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Epitope tag, Inserted expressed sequence, Recombinase) Mutations:    Insertion, Intragenic deletion   Oxtrtm3.1(Oxtr*,cre)Knis expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Oxtr (MGI:109147)   Mutation details: The part of exon 3 was replaced with a mouse Oxtr cDNA tagged with the hemagglutinin epitope at the 3' end (Oxtr CDNA), internal ribosomal entery site (IRES) and cre, and a FRT flanked pgk-neo cassette was inserted in intron 3 via homologous recombination. The neo cassette was then removed by flippase mediated recombination. (J:287190)

Activity:	Tissue activity of this recombinase allele
Driver:	Oxtr (mouse) Summary of all recombinase alleles driven by Oxtr. Comparative matrix view of recombinase activities Alliance mouse Oxtr gene page

In Mice Carrying this Mutation:

6 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Oxtr Mutation:	40 strains or lines available

Original:	J:287190 Hidema S, et al., Generation of Oxtr cDNA(HA)-Ires-Cre Mice for Gene Expression in an Oxytocin Receptor Specific Manner. J Cell Biochem. 2016 May;117(5):1099-111
All:	5 reference(s)