Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Ift140tm1.1(cre/ERT2)Yaos
Name:	intraflagellar transport 140; targeted mutation 1.1, Yao Sun
MGI ID:	MGI:6718291
Synonyms:	Ift140-creER
Gene:	Ift140  Location: Chr17:25235056-25318461 bp, + strand  Genetic Position: Chr17, 12.53 cM
Alliance:	Ift140tm1.1(cre/ERT2)Yaos page

Germline Transmission:	Earliest citation of germline transmission: J:304652
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutation:    Insertion   Ift140tm1.1(cre/ERT2)Yaos expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Ift140 (MGI:2146906)   Mutation details: A T2A-cre/ERT2-P2A-LacZ and a Rox-flanked neo selection cassette were inserted into the 3' UTR of the Ift140 gene by homologous recombination in ES cells. The neo cassette was removed subsequently. (J:304652)

Activity:	Tissue activity of this recombinase allele
Driver:	Ift140 (mouse) Summary of all recombinase alleles driven by Ift140. Alliance mouse Ift140 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ift140 Mutation:	71 strains or lines available

Original:	J:304652 Chen Y, et al., Lineage tracing of cells expressing the ciliary gene IFT140 during bone development. Dev Dyn. 2021 Apr;250(4):574-583
All:	1 reference(s)