Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Tcf7-EGFP,-cre/ERT2)#Held
Name:	transgene insertion, Werner Held
MGI ID:	MGI:6717277
Synonyms:	Tg(Tcf7CreER-GFP)Whe
Transgene:	Tg(Tcf7-EGFP,-cre/ERT2)#Held  Location: unknown
Alliance:	Tg(Tcf7-EGFP,-cre/ERT2)#Held page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inducible, Recombinase, Reporter) Inducer:    tamoxifen Mutation:    Insertion   Tg(Tcf7-EGFP,-cre/ERT2)#Held expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Tcf7 (MGI:98507)   Mutation details: The transgene consisting of a bacterial artificial chromosome (BAC) containing the entire Tcf7 locus (RP23-223A11) with an EGFP-T2A-CreERT2-polyA fusion gene inserted into the endogenous translation start codon present in exon Ia of the Tcf7 locus was injected into a pronucleus of a fertilized B6 oocytes. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:305277)

Activity:	Tissue activity of this recombinase allele
Driver:	Tcf7 (mouse) Summary of all recombinase alleles driven by Tcf7. Alliance mouse Tcf7 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:305277 Pais Ferreira D, et al., Central memory CD8(+) T cells derive from stem-like Tcf7(hi) effector cells in the absence of cytotoxic differentiation. Immunity. 2020 Nov 17;53(5):985-1000.e11
All:	1 reference(s)