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Gene Expression Data
Assay Details
Assay
Reference: J:221163 Lim J, et al., BMP-Smad4 signaling is required for precartilaginous mesenchymal condensation independent of Sox9 in the mouse. Dev Biol. 2015 Apr 1;400(1):132-8
Assay type: RNA in situ
MGI Accession ID: MGI:6715567
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Results
Specimen 5A E10.5 WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present 5A E10.5 WT
Specimen 5A E10.5 PS4: embryonic day 10.5; Smad4tm2.1Cxd/Smad4tm2.1Cxd, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: forelimb bud Present 5A E10.5 PS4 Authors report expression was relatively normal in mutant at E10.5
Specimen 5A E12.0 WT: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: forearm Present 5A E12.0 WT Expression normally demarcates autopod and zeugopod elements.
TS20: hand Present 5A E12.0 WT Expression normally demarcates autopod and zeugopod elements.
TS20: upper arm mesenchyme Present Regionally restricted 5A E12.0 WT Expression in proximal mesenchyme.
Specimen 5A E12.0 PS4: embryonic day 12.0; Smad4tm2.1Cxd/Smad4tm2.1Cxd, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: forearm Ambiguous 5A E12.0 PS4 Expression largely undetectable in autopod and zeugopod regions.
TS20: hand Ambiguous 5A E12.0 PS4 Expression largely undetectable in autopod and zeugopod regions.
TS20: upper arm mesenchyme Weak Regionally restricted 5A E12.0 PS4 Lower level of expression in proximal mesenchyme
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory