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Gene Expression Data
Assay Details
Assay
Reference: J:263030 Hu J, et al., WDR1-regulated actin dynamics is required for outflow tract and right ventricle development. Dev Biol. 2018 Jun 15;438(2):124-137
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6715547
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: clone 39.4D5
Results
Specimen S4A: embryonic day 9.5; Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1+ (more )
Note: Conditional mutant. Double labeled: red - Isl1; gray - Mki67 (assay MGI:6715544).
Structure Level Pattern Image Note
TS15: outflow tract Present S4A
TS15: primitive ventricle Present S4A
Specimen S4B: embryonic day 9.5; Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1tm1.1Zzy (more )
Note: Conditional mutant. Double labeled: red - Isl1; gray - Mki67 (assay MGI:6715544).
Structure Level Pattern Image Note
TS15: outflow tract Present S4B No difference in number of expressing cells between CTL and shfKO embryos.
TS15: primitive ventricle Present S4B No difference in number of expressing cells between CTL and shfKO embryos.
Specimen E10.5 CTL not shown: embryonic day 10.5; Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: outflow tract Present
TS17: primitive ventricle Present
Specimen E10.5 shfKO not shown: embryonic day 10.5; Tg(Mef2c-cre)2Blk/0, Wdr1tm1.1Zzy/Wdr1tm1.1Zzy (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: outflow tract Present No difference in number of expressing cells between CTL and shfKO embryos.
TS17: primitive ventricle Present No difference in number of expressing cells between CTL and shfKO embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
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