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Gene Expression Data
Assay Details
Assay
Reference: J:103603 Pan Y, et al., Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis. Dev Biol. 2005 Oct 15;286(2):472-82
Assay type: RNA in situ
MGI Accession ID: MGI:6715206
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Probe: Fgf8 probe122
Probe preparation: labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 7A fl-1: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 7A fl-1
Specimen 7A fl-2: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 7A fl-2
Specimen 7B fl-1: embryonic day 11.5; Notch1tm2Rko/Notch1tm2Rko, Notch2tm1Rko/Notch2tm1Rko, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 7B fl-1 No noticeable change in expression compared to wild type.
Specimen 7B fl-2: embryonic day 11.5; Notch1tm2Rko/Notch1tm2Rko, Notch2tm1Rko/Notch2tm1Rko, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: handplate apical ectodermal ridge Present 7B fl-2 No noticeable change in expression compared to wild type.
Specimen 7C hl-1: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present 7C hl-1
Specimen 7C hl-2: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present 7C hl-2
Specimen 7D hl-1: embryonic day 11.5; Notch1tm2Rko/Notch1tm2Rko, Notch2tm1Rko/Notch2tm1Rko, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Strong 7D hl-1 Expression upregulated in AER of hindlimbs.
Specimen 7D hl-2: embryonic day 11.5; Notch1tm2Rko/Notch1tm2Rko, Notch2tm1Rko/Notch2tm1Rko, Tg(Msx2-cre)5Rem/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Strong 7D hl-2 Expression upregulated in AER of hindlimbs.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
MGI 6.24 		The Jackson Laboratory