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Gene Expression Data
Assay Details
Assay
Reference: J:272319 Tiveron MC, et al., Expression and function of CXCR7 in the mouse forebrain. J Neuroimmunol. 2010;224(1-2):72-9
Assay type: RNA in situ
MGI Accession ID: MGI:6715130
Gene symbol: Ackr3
Gene name: atypical chemokine receptor 3
Probe: Cxcr7 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 1A Expression was detected in the ventral telencephalon in the proliferative zones. Dorsal telencephalon was mainly devoid of staining.
TS20: medial ganglionic eminence Present Regionally restricted 1A Expression was detected in the ventricular zone and subventricular zone.
TS20: lateral ganglionic eminence Present Regionally restricted 1A Expression was detected in the ventral part.
TS20: cortical hem Present Regionally restricted 1A Expression was detected in a small number of cells.

Specimen 1B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 1B Expression in the subpallium formed two continuums. One was located between the ganglionic eminence and the ventral pial surface; these cells are likely to be olfactory tubercle neuron precursors migrating from the lateral ganglionic eminence. The second continuum of stained cells was positioned between the medial ganglionic eminence and the ventral cortex, suggestive of cortical interneurons generated in the medial ganglionic eminence and migrating towards the cortex.
TS20: cerebral cortex Present Regionally restricted 1B' , 1B Expression was detected in a superficial layer of cells.

Specimen 1C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Strong Regionally restricted 1C Expression was detected in the germinal zone.
TS21: cerebral cortex Present Regionally restricted 1C Expression was detected in dorsomedial cortex.
TS21: cerebral cortex marginal layer Present Regionally restricted 1C Expression was detected in the lateral cortex.
TS21: cerebral cortex subventricular zone Present Regionally restricted 1C Expression was detected in the lateral cortex.

Specimen 1D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex marginal layer Present 1D
TS23: cerebral cortex subventricular zone Present 1D
TS23: caudate-putamen Absent 1D

Specimen 1E: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: corpus striatum Present Regionally restricted 1E , 1E' Expression was detected in the striatal subventricular zone.
TS27: cortical plate Present Regionally restricted 1E Expression was concentrated in a deep and a superficial layer of the cortical plate.

Specimen 2C: embryonic day 12.5 (more )
Note: Double labeled: blue - Ackr3; brown - BrdU.
Structure Level Pattern Image Note
TS20: cerebral cortex Present Regionally restricted 2C Expression was detected in postmitotic cells.

Specimen 2D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cortical preplate Present 2D

Specimen 4A: postnatal day 2 (more )
Structure Level Pattern Image Note
TS27: cerebral cortex subventricular zone Present 4A
TS27: rostral migratory stream Present 4A


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory