Tg(Thy1-Usp14*C114A)5-40Swi
Transgene Detail
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Symbol: |
Tg(Thy1-Usp14*C114A)5-40Swi |
Name: |
transgene insertion 5-40, Scott Wilson |
MGI ID: |
MGI:6715064 |
Synonyms: |
TgUsp14CA |
Transgene: |
Tg(Thy1-Usp14*C114A)5-40Swi Location: unknown
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Alliance: |
Tg(Thy1-Usp14*C114A)5-40Swi page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Thy1-Usp14*C114A)5-40Swi expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Usp14 (MGI:1928898) |
Usp14*C114A |
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Mutation details: The transgenic construct contains a modified full length mouse Usp14 cDNA (including the Usp14 Kozak sequence) under the control of the pan-neuronal Thy1 (Thy1.2) promoter. The Usp14 sequence is modified to change the active site cysteine to an alanine (C114A) at position 114.
(J:306115)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:306115 Vaden JH, et al., Ubiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junction. Mol Neurodegener. 2015 Jan 10;10:3 |
All: |
1 reference(s) |
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