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Tg(Thy1-Usp14*C114A)5-40Swi
Transgene Detail
Summary
Symbol: Tg(Thy1-Usp14*C114A)5-40Swi
Name: transgene insertion 5-40, Scott Wilson
MGI ID: MGI:6715064
Synonyms: TgUsp14CA
Transgene: Tg(Thy1-Usp14*C114A)5-40Swi  Location: unknown  
Alliance: Tg(Thy1-Usp14*C114A)5-40Swi page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Thy1-Usp14*C114A)5-40Swi expresses 1 gene
 
Mutation detailsThe transgenic construct contains a modified full length mouse Usp14 cDNA (including the Usp14 Kozak sequence) under the control of the pan-neuronal Thy1 (Thy1.2) promoter. The Usp14 sequence is modified to change the active site cysteine to an alanine (C114A) at position 114. (J:306115)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:306115 Vaden JH, et al., Ubiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junction. Mol Neurodegener. 2015 Jan 10;10:3
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory