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Gene Expression Data
Assay Details
Assay
Reference: J:64996 Burgess RW, et al., Agrin isoforms with distinct amino termini. Differential expression, localization, and function. J Cell Biol. 2000 Oct 2;151(1):41-52
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6714280
Gene symbol: Agrn
Gene name: agrin
Antibody: anti-agrin
Results
Specimen 7A: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: brain blood vessel Present Regionally restricted 7A Expression in basal lamina of cerebral microvasculature.

Specimen 7B: embryonic day 18.0; AgrnGt(Ex192)Byg/AgrnGt(Ex192)Byg (more )
Structure Level Pattern Image Note
TS26: brain blood vessel Absent 7B

Specimen 7C: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: glomerular tuft Present Regionally restricted 7C Expression in glomerular basement membrane.

Specimen 7D: embryonic day 18.0; AgrnGt(Ex192)Byg/AgrnGt(Ex192)Byg (more )
Structure Level Pattern Image Note
TS26: glomerular tuft Absent 7D

Specimen 7E: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: optic nerve Present Regionally restricted 7E Expression in meningeal sheath - i.e. basal lamina of pia and sheath of optic nerve.
TS26: pia mater Present Regionally restricted 7E Expression in meningeal sheath - i.e. basal lamina of pia and sheath of optic nerve.

Specimen 7F: embryonic day 18.0; AgrnGt(Ex192)Byg/AgrnGt(Ex192)Byg (more )
Structure Level Pattern Image Note
TS26: optic nerve Absent 7F
TS26: pia mater Absent 7F

Specimen wild-type not shown: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: lung Present Regionally restricted Expression in basal lamina.
TS26: retina Present Regionally restricted Expression in basal lamina.
TS26: skin Present Regionally restricted Expression in basal lamina.

Specimen E16 LN/LN not shown: embryonic day 18.0; AgrnGt(Ex192)Byg/AgrnGt(Ex192)Byg (more )
Structure Level Pattern Image Note
TS26: lung Absent
TS26: retina Absent
TS26: skin Absent

Specimen neonate LN/LN not shown: postnatal newborn; AgrnGt(Ex192)Byg/AgrnGt(Ex192)Byg (more )
Structure Level Pattern Image Note
TS27: lung Absent
TS27: retina Absent
TS27: skin Absent

Specimen 8E: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: intercostal muscle Present Regionally restricted 8E Expression in extra-synaptic basal lamina of myotubes.

Specimen 8F: embryonic day 18.0; AgrnGt(Ex192)Byg/AgrnGt(Ex192)Byg (more )
Structure Level Pattern Image Note
TS26: intercostal muscle Absent 8F All muscle expression is eliminated in mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory