Gene Expression Data
Assay Details
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Assay
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Reference:
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J:242197
Jakubiczka-Smorag J, et al., Mouse model for molybdenum cofactor deficiency type B recapitulates the phenotype observed in molybdenum cofactor deficient patients. Hum Genet. 2016 Jul;135(7):813-26
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6712797
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Gene symbol:
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Casp3
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Gene name:
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caspase 3
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Results
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Specimen
10a Mocs2+/+ Hippocampus:
postnatal adult
(more  )
Specimen
10a Mocs2+/+ Hippocampus:
(close  )
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Genetic Background:
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involves: C57BL/6NTac
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
10a Mocs2+/- Hippocampus:
(close )
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Genetic Background:
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involves: C57BL/6NTac
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Mutant Allele(s):
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Mocs2tm1(KOMP)Vlcg/Mocs2+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hippocampus |
Present |
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10a Hippocampus Mocs2+/-
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Mocs2+/- mice displayed elevated numbers of neuronal cells expressing Casp3.
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Specimen
10a Mocs2-/- Hippocampus:
(close )
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Genetic Background:
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involves: C57BL/6NTac
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Mutant Allele(s):
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Mocs2tm1(KOMP)Vlcg/Mocs2tm1(KOMP)Vlcg
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hippocampus |
Present |
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10a Hippocampus Mocs2-/-
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Mocs2-/- mice displayed elevated numbers of neuronal cells expressing Casp3.
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Specimen
10a Mocs2+/+ CA1:
postnatal adult
(more )
Specimen
10a Mocs2+/+ CA1:
(close )
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Genetic Background:
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involves: C57BL/6NTac
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
10a Mocs2+/- CA1:
(close )
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Genetic Background:
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involves: C57BL/6NTac
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Mutant Allele(s):
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Mocs2tm1(KOMP)Vlcg/Mocs2+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hippocampus CA1 |
Present |
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10a CA1 Mocs2+/-
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Mocs2+/- mice displayed elevated numbers of neuronal cells expressing Casp3.
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Specimen
10a Mocs2-/- CA1:
(close )
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Genetic Background:
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involves: C57BL/6NTac
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Mutant Allele(s):
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Mocs2tm1(KOMP)Vlcg/Mocs2tm1(KOMP)Vlcg
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hippocampus CA1 |
Present |
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10a CA1 Mocs2-/-
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Mocs2-/- mice displayed elevated numbers of neuronal cells expressing Casp3.
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Specimen
10a Mocs2+/+ DG:
postnatal adult
(more )
Specimen
10a Mocs2+/+ DG:
(close )
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Genetic Background:
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involves: C57BL/6NTac
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
10a Mocs2+/- DG:
(close )
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Genetic Background:
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involves: C57BL/6NTac
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Mutant Allele(s):
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Mocs2tm1(KOMP)Vlcg/Mocs2+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: dentate gyrus |
Present |
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10a DG Mocs2+/-
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Mocs2+/- mice displayed elevated numbers of neuronal cells expressing Casp3.
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Specimen
10a Mocs2-/- DG:
(close )
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Genetic Background:
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involves: C57BL/6NTac
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Mutant Allele(s):
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Mocs2tm1(KOMP)Vlcg/Mocs2tm1(KOMP)Vlcg
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: dentate gyrus |
Present |
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10a DG Mocs2-/-
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Mocs2-/- mice displayed elevated numbers of neuronal cells expressing Casp3.
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Specimen
10a Mocs2+/+ Cortex:
postnatal adult
(more )
Specimen
10a Mocs2+/+ Cortex:
(close )
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Genetic Background:
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involves: C57BL/6NTac
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
10a Mocs2+/- Cortex:
(close )
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Genetic Background:
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involves: C57BL/6NTac
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Mutant Allele(s):
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Mocs2tm1(KOMP)Vlcg/Mocs2+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cerebral cortex |
Present |
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10a Cortex Mocs2+/-
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Mocs2+/- mice displayed elevated numbers of neuronal cells expressing Casp3.
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Specimen
10a Mocs2-/- Cortex:
(close )
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Genetic Background:
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involves: C57BL/6NTac
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Mutant Allele(s):
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Mocs2tm1(KOMP)Vlcg/Mocs2tm1(KOMP)Vlcg
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cerebral cortex |
Present |
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10a Cortex Mocs2-/-
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Mocs2-/- mice displayed elevated numbers of neuronal cells expressing Casp3.
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Specimen
10a Mocs2+/+ Brainstem (pons):
postnatal adult
(more )
Specimen
10a Mocs2+/+ Brainstem (pons):
(close )
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Genetic Background:
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involves: C57BL/6NTac
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: pons |
Ambiguous |
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10a Brainstem (pons) Mocs2+/+
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Specimen
10a Mocs2+/- Brainstem (pons):
postnatal adult; Mocs2tm1(KOMP)Vlcg/Mocs2 +
(more )
Specimen
10a Mocs2+/- Brainstem (pons):
(close )
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Genetic Background:
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involves: C57BL/6NTac
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Mutant Allele(s):
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Mocs2tm1(KOMP)Vlcg/Mocs2+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: pons |
Present |
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10a Brainstem (pons) Mocs2+/-
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Mocs2+/- mice displayed elevated numbers of neuronal cells expressing Casp3.
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Specimen
10a Mocs2-/- Brainstem (pons):
(close )
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Genetic Background:
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involves: C57BL/6NTac
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Mutant Allele(s):
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Mocs2tm1(KOMP)Vlcg/Mocs2tm1(KOMP)Vlcg
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: pons |
Present |
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10a Brainstem (pons) Mocs2-/-
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Mocs2-/- mice displayed elevated numbers of neuronal cells expressing Casp3.
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Analysis Tools