Summary | Transgene origin | Transgene description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tg(Neurod4-cre/ERT2)D4ATahi
Name:	transgene insertion D4A, Tatsumi Hirata
MGI ID:	MGI:6712715
Synonyms:	Neurod4CreER(D4A)
Transgene:	Tg(Neurod4-cre/ERT2)D4ATahi  Location: unknown
Alliance:	Tg(Neurod4-cre/ERT2)D4ATahi page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Tg(Neurod4-cre/ERT2)D4ATahi expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Neurod4 (MGI:108055)   Mutation details: The transgene was constructed using a genomic BAC clone RP23-55O18 encoding the mouse neurod4 gene by inserting a CreERT2 cassette at the first ATG sequence of exon2 and the loxP site in the vector backbone (pBACe3.6) was deleted by replacement with the zeocin resistance gene. The five mouse lines that independently received the transgene integration were then assayed for the Cre recombinase activities. Through this screen, one line (G1C) was selected by the highest recombination rate. (J:306016)

Activity:	Tissue activity of this recombinase allele
Driver:	Neurod4 (mouse) Summary of all recombinase alleles driven by Neurod4. Alliance mouse Neurod4 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:306016 Hirata T, et al., NeuroGT: A brain atlas of neurogenic tagging CreER drivers for birthdate-based classification and manipulation of mouse neurons. Cell Rep Med. 2021 Jul;
All:	1 reference(s)