Tg(Cdhr1-tTA)#Tahi
Transgene Detail
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| Symbol: |
Tg(Cdhr1-tTA)#Tahi |
| Name: |
transgene insertion, Tatsumi Hirata |
| MGI ID: |
MGI:6712689 |
| Synonyms: |
Cdhr1tTA |
| Transgene: |
Tg(Cdhr1-tTA)#Tahi Location: unknown
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| Alliance: |
Tg(Cdhr1-tTA)#Tahi page
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| Transgene Type: |
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Transgenic (Transactivator) |
| Mutation: |
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Insertion
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Mutation details: The transgene was established using a mouse genomic BAC clone RP23-55P20, which encodes cadherin-related family member (Cdhr)1 gene by inserting a loxP-LacZ-loxP-tTA cassette at 25 bp upstream of the translation initiation site of this gene. In this cassette, the LacZ gene followed by a transcription termination site was flanked by loxP sequences and used as a STOP sequence, which followed by the tetracycline-controlled transactivator (tTA) gene in an optimized form for mammalian expression. The original loxP site in the vector backbone was subsequently deleted using p23loxZeo. Among the six independent transgenic lines obtained, one unnumbered line was characterized by the OB-specific strongest expression of the internal LacZ gene.
(J:288786)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:288786 Hirata T, et al., A Novel Birthdate-Labeling Method Reveals Segregated Parallel Projections of Mitral and External Tufted Cells in the Main Olfactory System. eNeuro. 2019 Nov/Dec;6(6):ENEURO.0234-19.2019 |
| All: |
1 reference(s) |
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