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Gene Expression Data
Assay Details
Assay
Reference: J:241850 Naiman N, et al., Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 May 22;41(4):349-365.e3
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6711833
Gene symbol: Cdkn1c
Gene name: cyclin dependent kinase inhibitor 1C
Antibody: Anti-p57Kip2 (ab4058)
Detection system: Secondary antibody coupled to DyLight
Results
Specimen 4U: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Cdkn1c; red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS26: inner medullary interstitium Present Regionally restricted 4U Expression is seen in a subset of inner renal medullary interstitial cells around the collecting duct system.
Specimen 4V: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Cdkn1c; red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS26: inner medullary interstitium Present 4V
Specimen S3O: embryonic day 15.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Cdkn1c; red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS23: renal medullary interstitium Present Regionally restricted S3O Expression is seen in a subset of inner renal medullary interstitial cells.
Specimen S3P: embryonic day 15.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Cdkn1c; red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS23: renal medullary interstitium Present Regionally restricted S3P Expression is seen in a subset of inner renal medullary interstitial cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory