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Gene Expression Data
Assay Details
Assay
Reference: J:241850 Naiman N, et al., Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 May 22;41(4):349-365.e3
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6711810
Gene symbol: Pax2
Gene name: paired box 2
Antibody: anti-Pax2 (clone 3C7; H00005076-M01)
Detection system: Secondary antibody coupled to DyLight
Results
Specimen 1A/D: embryonic day 10.5 (more )
Note: Triple labeled: red - Pax2; green - Six2 (assay MGI:6711765); blue - Foxd1 (assay MGI:6711779)
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Present 1D , 1A
TS17: nephric duct Present 1D , 1A
TS17: ureteric bud Present 1D , 1A
Specimen 1E/H: embryonic day 11.5 (more )
Note: Triple labeled: red - Pax2; green - Six2 (assay MGI:6711765); blue - Foxd1 (assay MGI:6711779)
Structure Level Pattern Image Note
TS19: cap mesenchyme Present 1H , 1E
TS19: ureteric tip Present 1H , 1E
Specimen 1I/L: embryonic day 15.5 (more )
Note: Triple labeled: red - Pax2; green - Six2 (assay MGI:6711765); blue - Foxd1 (assay MGI:6711779)
Structure Level Pattern Image Note
TS23: cap mesenchyme Present 1L , 1I
TS23: nephron Present Regionally restricted 1L , 1I Expression is present in a subset of differentiating nephron cells.
TS23: ureteric tip Present 1L , 1I
Specimen S2A''/A''''/A''''': embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: blue - Pax2; red - Six2 (assay MGI:6711765); green - Cre reporter
Structure Level Pattern Image Note
TS26: ureteric tip Present S2A'''' , S2A''''' , S2A''
Specimen S2B''/B''''/B''''': embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: blue - Pax2; red - Six2 (assay MGI:6711765); green - Cre reporter
Structure Level Pattern Image Note
TS26: ureteric tip Present S2B'' , S2B''''' , S2B'''' Ureteric tips are rare in the mutants.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory