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Gene Expression Data
Assay Details
Assay
Reference: J:241850 Naiman N, et al., Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 May 22;41(4):349-365.e3
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6711802
Gene symbol: Pdgfrb
Gene name: platelet derived growth factor receptor, beta polypeptide
Antibody: anti-Cd140b/Pdgfrb (APB5)
Detection system: Secondary antibody coupled to DyLight
Results
Specimen 2G: embryonic day 18.5; Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Pdgfrb; green - Pax2 (assay MGI:6711811); white - cytokeratin
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present Widespread 2G
Specimen 2H: embryonic day 18.5; Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Pdgfrb; green - Pax2 (assay MGI:6711811); white - cytokeratin
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present 2H
Specimen 4Q: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Pdgfrb; red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS26: inner medullary interstitium Present Widespread 4Q
Specimen 4R: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Pdgfrb; red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS26: inner medullary interstitium Present 4R
Specimen S2G: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: blue - Pdgfrb; green - Foxd1 (assay MGI:6711779); red - Cre reporter
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present S2G
Specimen S2H: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: blue - Pdgfrb; green - Foxd1 (assay MGI:6711779); red - Cre reporter
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present S2H
Specimen S3I'/I'': embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: blue - Pdgfrb; green - Foxd1 (assay MGI:6711779); red - Cre reporter
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present S3I' , S3I''
Specimen S3J'/J'': embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: blue - Pdgfrb; green - Foxd1 (assay MGI:6711779); red - Cre reporter
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present S3J'' , S3J'
Specimen S3K: embryonic day 15.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Pdgfrb; red - red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS23: renal medullary interstitium Present Widespread S3K
Specimen S3L: embryonic day 15.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Pdgfrb; red - red - Cre reporter; white - cytokeratin
Structure Level Pattern Image Note
TS23: renal medullary interstitium Present S3L There is ectopic expression in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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