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Gene Expression Data
Assay Details
Assay
Reference: J:241850 Naiman N, et al., Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development. Dev Cell. 2017 May 22;41(4):349-365.e3
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6711779
Gene symbol: Foxd1
Gene name: forkhead box D1
Antibody: anti-Foxd1 (C-19; sc-47585)
Detection system: Secondary antibody coupled to DyLight
Results
Specimen 1C/D: embryonic day 10.5 (more )
Note: Triple labeled: blue - Foxd1; red - Pax2 (assay MGI:6711810); green - Six2 (assay MGI:6711765)
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Weak Single cells 1C , 1D Expression is seen in a few mesenchymal cells.
Specimen 1G/H: embryonic day 11.5 (more )
Note: Triple labeled: blue - Foxd1; red - Pax2 (assay MGI:6711810); green - Six2 (assay MGI:6711765)
Structure Level Pattern Image Note
TS19: mesenchyme of metanephros Present Scattered 1G , 1H Expression is seen in scattered renal cortical stroma cells.
Specimen 1K/L: embryonic day 15.5 (more )
Note: Triple labeled: blue - Foxd1; red - Pax2 (assay MGI:6711810); green - Six2 (assay MGI:6711765)
Structure Level Pattern Image Note
TS23: renal cortical interstitium Present 1L , 1K Expression is seen in renal cortical stroma cells.
Specimen 2I: embryonic day 18.5; Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Foxd1; green - Six2 (assay MGI:6711765); white - cytokeratin
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present 2I
Specimen 2J: embryonic day 18.5; Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Foxd1; green - Six2 (assay MGI:6711765); white - cytokeratin
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present 2J
Specimen 4I: embryonic day 13.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Foxd1; red - Cre reporter; white - Liv2 antigen
Structure Level Pattern Image Note
TS21: renal interstitium Present 4I Expression is seen in renal cortical stroma.
Specimen 4J: embryonic day 13.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Foxd1; red - Cre reporter; white - Liv2 antigen
Structure Level Pattern Image Note
TS21: renal interstitium Present 4J Expression is seen in renal cortical stroma; it is in ectopic locations in the mutant.
Specimen 4K: embryonic day 15.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Foxd1; red - Cre reporter; white - Liv2 antigen
Structure Level Pattern Image Note
TS23: renal cortical interstitium Present 4K
Specimen 4L: embryonic day 15.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Foxd1; red - Cre reporter; white - Liv2 antigen
Structure Level Pattern Image Note
TS23: renal cortical interstitium Present 4L Expression is seen in ectopic locations.
Specimen 4M: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Foxd1; red - Cre reporter; white - Liv2 antigen
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present 4M
Specimen 4N: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Foxd1; red - Cre reporter; white - Liv2 antigen
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present 4N Expression is seen in ectopic locations.
Specimen 4O: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Foxd1; red - Cre reporter; white - Liv2 antigen
Structure Level Pattern Image Note
TS26: renal medullary interstitium Absent 4O
Specimen 4P: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Foxd1; red - Cre reporter; white - Liv2 antigen
Structure Level Pattern Image Note
TS26: renal medullary interstitium Present 4P
Specimen 5C/E/G: embryonic day 13.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Foxd1; green - Six2 (assay MGI:6711765); blue - Cre reporter
Structure Level Pattern Image Note
TS21: renal interstitium Present 5E , 5C , 5G Expression is seen in renal cortical interstitial cells.
Specimen 5D/F/H: embryonic day 13.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Foxd1; green - Six2 (assay MGI:6711765); blue - Cre reporter
Structure Level Pattern Image Note
TS21: renal interstitium Present 5D , 5H , 5F Expression is seen in renal cortical interstitial cells.
Specimen S2C: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: blue - Foxd1; green - Six2 (assay MGI:6711765); red - Cre reporter
Structure Level Pattern Image Note
TS26: nephrogenic interstitium Present S2C
Specimen S2D: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: blue - Foxd1; green - Six2 (assay MGI:6711765); red - Cre reporter
Structure Level Pattern Image Note
TS26: nephrogenic interstitium Present S2D
Specimen S2E: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Foxd1; blue - Liv2 antigen; red - Cre reporter
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present S2E
Specimen S2F: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Foxd1; blue - Liv2 antigen; red - Cre reporter
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present S2F
Specimen S2G: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Foxd1; blue - Pdgfrb (assay MGI:6711802); red - Cre reporter
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present S2G
Specimen S2H: embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Foxd1; blue - Pdgfrb (assay MGI:6711802); red - Cre reporter
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present S2H
Specimen S3I/I'': embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Foxd1; blue - Pdgfrb (assay MGI:6711802); red - Cre reporter
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present S3I'' , S3I
Specimen S3J/J'': embryonic day 18.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: green - Foxd1; blue - Pdgfrb (assay MGI:6711802); red - Cre reporter
Structure Level Pattern Image Note
TS26: renal cortical interstitium Present S3J , S3J''
Specimen S3Q'/Q''/Q''': embryonic day 15.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2+, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Foxd1; green - Six2 (assay MGI:6711765); blue - Cre reporter
Structure Level Pattern Image Note
TS23: renal cortical interstitium Present S3Q' , S3Q''' , S3Q''
Specimen S3R'/R''/R''': embryonic day 15.5; Gt(ROSA)26Sortm1Sor/Gt(ROSA)26Sor+, Pax2tm1.1Akio/Pax2tm1.2Akio, Tg(Six2-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant. Triple labeled: red - Foxd1; green - Six2 (assay MGI:6711765); blue - Cre reporter
Structure Level Pattern Image Note
TS23: renal cortical interstitium Present S3R'' , S3R''' , S3R'
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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