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Gene Expression Data
Assay Details
Assay
Reference: J:286303 Buckley DM, et al., Gbx1 and Gbx2 Are Essential for Normal Patterning and Development of Interneurons and Motor Neurons in the Embryonic Spinal Cord. J Dev Biol. 2020 Apr 1;8(2)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6705110
Gene symbol: Casp3
Gene name: caspase 3
Antibody: Anti-Caspase3
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 5A: embryonic day 13.5 (more )
Note: Lumber spinal cord. Double labeled: green - Casp3; red - Isl1 (assay MGI:6705111).
Structure Level Pattern Image Note
TS21: spinal cord Present Single cells 5A A few cells were immunopositive for Casp3. However, none of these cells co-localized with Isl1-immunopositive cells.
Specimen 5B: embryonic day 13.5; Gbx1tm1.1Stwt/Gbx1tm1.1Stwt (more )
Note: Lumber spinal cord. Double labeled: green - Casp3; red - Isl1 (assay MGI:6705111).
Structure Level Pattern Image Note
TS21: spinal cord Present Regionally restricted 5B Some of the Casp3-positive cells were also immunopositive for Isl1 in the Gbx1 mutant.
Specimen 5C: embryonic day 13.5; Gbx2tm1.1Mrt/Gbx2tm1.1Mrt (more )
Note: Lumber spinal cord. Double labeled: green - Casp3; red - Isl1 (assay MGI:6705111).
Structure Level Pattern Image Note
TS21: spinal cord Present Regionally restricted 5C Some of the Casp3-positive cells were also immunopositive for Isl1 in the Gbx2 mutant at E13.5.
Specimen 5D: embryonic day 13.5; Gbx1tm1.1Stwt/Gbx1tm1.1Stwt, Gbx2tm1.1Mrt/Gbx2tm1.1Mrt (more )
Note: Lumber spinal cord. Double labeled: green - Casp3; red - Isl1 (assay MGI:6705111).
Structure Level Pattern Image Note
TS21: spinal cord Present Regionally restricted 5D Some of the Casp3-positive cells were also immunopositive for Isl1 in the Gbx dKO mutant.
Specimen 5E: embryonic day 14.5 (more )
Note: Lumber spinal cord. Double labeled: green - Casp3; red - Isl1 (assay MGI:6705111).
Structure Level Pattern Image Note
TS22: spinal cord Present Single cells 5E A few cells were immunopositive for Casp3. However, none of these cells co-localized with Isl1-immunopositive cells.
Specimen 5F: embryonic day 14.5; Gbx1tm1.1Stwt/Gbx1tm1.1Stwt (more )
Note: Lumber spinal cord. Double labeled: green - Casp3; red - Isl1 (assay MGI:6705111).
Structure Level Pattern Image Note
TS22: spinal cord Present Regionally restricted 5F Some of the Casp3-positive cells were also immunopositive for Isl1 in the Gbx1 mutant.
Specimen 5G: embryonic day 14.5; Gbx2tm1.1Mrt/Gbx2tm1.1Mrt (more )
Note: Lumber spinal cord. Double labeled: green - Casp3; red - Isl1 (assay MGI:6705111).
Structure Level Pattern Image Note
TS22: spinal cord Absent 5G
Specimen 5H: embryonic day 14.5; Gbx1tm1.1Stwt/Gbx1tm1.1Stwt, Gbx2tm1.1Mrt/Gbx2tm1.1Mrt (more )
Note: Lumber spinal cord. Double labeled: green - Casp3; red - Isl1 (assay MGI:6705111).
Structure Level Pattern Image Note
TS22: spinal cord Present Regionally restricted 5H Some of the Casp3-positive cells were also immunopositive for Isl1 in the Gbx dKO mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
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