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Gene Expression Data
Assay Details
Assay
Reference: J:301228 Laugel-Haushalter V, et al., From the transcription of genes involved in ectodermal dysplasias to the understanding of associated dental anomalies. Mol Syndromol. 2012 Oct;3(4):158-68
Assay type: RNA in situ
MGI Accession ID: MGI:6696299
Gene symbol: Map2k1
Gene name: mitogen-activated protein kinase kinase 1
Probe: Map2k1 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4E: embryonic day 14.5 (more )
Note: Cap stage tooth.
Structure Level Pattern Image Note
TS22: cap stage tooth Present 4E
TS22: tooth epithelium Present 4E
TS22: tooth mesenchyme Present 4E
Specimen 4F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: incisor mesenchyme Present 4F
TS24: inner enamel epithelium Present 4F
TS24: molar mesenchyme Present 4F
TS24: outer enamel epithelium Present 4F
TS24: incisor Present Regionally restricted 4F Expression is in the mesenchyme and the epithelial inner, outer and loop areas.
TS24: molar Present Regionally restricted 4F Expression is in the mesenchyme and the epithelial inner, outer and loop areas.
Specimen 4G: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: tooth mesenchyme Present 4G
Specimen 5E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: submandibular gland epithelium Present 5E
Specimen 5J: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa follicle Strong Regionally restricted 5J Expression is in the epithelial layer of the vibrissae follicle shafts.
Specimen Table 2 E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral epithelium Present Regionally restricted Expression is in the oral epithelium at the site of incisors and first molars.
TS20: tooth Present Regionally restricted Expression is in the dental lamina of incisors and first molars.
Specimen Table 2 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: incisor dental lamina Present Regionally restricted Expression is in the gubernaculum.
TS22: molar dental lamina Present Regionally restricted Expression is in the gubernaculum of the first and second molar.
TS22: incisor dental papilla Present
TS22: incisor enamel organ Present
TS22: molar enamel organ Present
TS22: enamel knot Present Regionally restricted Expression is in the inner dental epithelium of the incisor and first and second molar.
TS22: incisor Present Regionally restricted Expression is in the inner dental epithelium of the incisor and first and second molar.
TS22: molar Present Regionally restricted Expression is in the inner dental epithelium of the incisor and first and second molar.
TS22: molar dental papilla Present Regionally restricted Expression is in the dental papilla of the first and second molar.
Specimen Table 2 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: molar dental lamina Present Regionally restricted Expression is in the gubernaculum of the first molar.
TS24: cervical loop Present Incisor and first molar.
TS24: incisor Present Incisor and first molar.
TS24: incisor dental papilla Present Incisor and first molar.
TS24: inner enamel epithelium Present Incisor and first molar.
TS24: molar Present Incisor and first molar.
TS24: molar dental papilla Present Incisor and first molar.
TS24: outer enamel epithelium Present Incisor and first molar.
Specimen Table 2 E19.5 (newborn): postnatal newborn (more )
Note: The authors speicfy day E19.5 as the day of birth.
Structure Level Pattern Image Note
TS27: incisor dental papilla Present
TS27: molar dental papilla Present First and second molar.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory