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Gene Expression Data
Assay Details
Assay
Reference: J:301228 Laugel-Haushalter V, et al., From the transcription of genes involved in ectodermal dysplasias to the understanding of associated dental anomalies. Mol Syndromol. 2012 Oct;3(4):158-68
Assay type: RNA in situ
MGI Accession ID: MGI:6696298
Gene symbol: Ercc3
Gene name: excision repair cross-complementing rodent repair deficiency, complementation group 3
Probe: Ercc3 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: enamel organ Present 4A
TS22: incisor epithelium Present 4A
TS22: oral epithelium Present 4A
TS22: incisor mesenchyme Weak 4A
TS22: molar mesenchyme Weak 4A
Specimen 4B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: enamel organ Present 4B
TS24: incisor mesenchyme Weak 4B
TS24: molar mesenchyme Weak 4B
Specimen 4C: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: cervical loop Present Regionally restricted 4C Expression is higher in the labial area within the epithelial loop and facing mesenchyme.
TS27: incisor Present Regionally restricted 4C Expression is higher in the labial area within the epithelial loop and facing mesenchyme.
TS27: enamel organ Present Regionally restricted 4C Expression is in preameloblasts and is absent in the most differentiated epithelial cells.
Specimen 5C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: submandibular gland epithelium Present 5C
Specimen 5H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa follicle Absent 5H
Specimen Table 2 E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral epithelium Present Regionally restricted Expression is in the oral epithelium at the site of incisors.
TS20: tooth Present Regionally restricted Expression is in the dental lamina and mesenchyme of incisors and first molars.
Specimen Table 2 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: incisor dental papilla Present
TS22: incisor enamel organ Present
TS22: molar dental papilla Present
TS22: molar enamel organ Present
TS22: inner enamel epithelium Present Regionally restricted Expression is in the inner dental epithelium of the incisor and first molar.
Specimen Table 2 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: incisor Present Incisor, first, and second molar.
TS24: incisor dental papilla Present Incisor, first, and second molar.
TS24: inner enamel epithelium Present Incisor, first, and second molar.
TS24: molar Present Incisor, first, and second molar.
TS24: molar dental papilla Present Incisor, first, and second molar.
Specimen Table 2 E19.5 (newborn): postnatal newborn (more )
Note: The authors speicfy day E19.5 as the day of birth.
Structure Level Pattern Image Note
TS27: inner enamel epithelium Present Regionally restricted First and second molar.
TS27: molar Present Regionally restricted First and second molar.
TS27: enamel organ Present Regionally restricted Expression is in preameloblasts in the incisor and first molar.
TS27: cervical loop Present Incisor, first, and second molar.
TS27: molar dental papilla Present First and second molar.
TS27: incisor dental papilla Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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