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Gene Expression Data
Assay Details
Assay
Reference: J:301228 Laugel-Haushalter V, et al., From the transcription of genes involved in ectodermal dysplasias to the understanding of associated dental anomalies. Mol Syndromol. 2012 Oct;3(4):158-68
Assay type: RNA in situ
MGI Accession ID: MGI:6696297
Gene symbol: Nfkbia
Gene name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
Probe: Nfkbia probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral epithelium Present 3A
TS20: tooth Present Regionally restricted 3A Expression is in the dental lamina.
Specimen 3B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral epithelium Present 3B
TS20: tooth Present Regionally restricted 3B Expression is in the dental lamina.
Specimen 3C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: enamel knot Strong 3C
TS22: enamel organ Present Scattered 3C
Specimen 3D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: enamel knot Strong 3D
TS22: enamel organ Present Scattered 3D
Specimen 3E: embryonic day 16.5 (more )
Note: Bell stage of tooth development.
Structure Level Pattern Image Note
TS24: cervical loop Present 3E
TS24: inner enamel epithelium Present 3E
TS24: outer enamel epithelium Present 3E
Specimen 3F: embryonic day 16.5 (more )
Note: Bell stage of tooth development.
Structure Level Pattern Image Note
TS24: cervical loop Present 3F
TS24: inner enamel epithelium Present 3F
TS24: outer enamel epithelium Present 3F
Specimen 3G: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: enamel organ Present Regionally restricted 3G Expression is in preameloblasts.
TS27: inner enamel epithelium Present 3G
TS27: outer enamel epithelium Present 3G
TS27: cervical loop Present Regionally restricted 3G Expression is in the epithelial loops of the second molars.
TS27: molar Present Regionally restricted 3G Expression is in the epithelial loops of the second molars.
TS27: dental pulp Present Regionally restricted 3G Expression is in odontoblasts.
Specimen 3H: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: enamel organ Present Regionally restricted 3H Expression is in preameloblasts.
TS27: inner enamel epithelium Present 3H
TS27: outer enamel epithelium Present 3H
TS27: cervical loop Present Regionally restricted 3H Expression is in the epithelial loops of the second molars.
TS27: molar Present Regionally restricted 3H Expression is in the epithelial loops of the second molars.
TS27: dental pulp Present Regionally restricted 3H Expression is in odontoblasts.
Specimen 5B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: submandibular gland epithelium Present 5B
Specimen 5G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa follicle Weak Regionally restricted 5G Expression is discontinupus in the epithelial layer of the vibrissae follicle shafts.
Specimen Table 2 E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral epithelium Present Regionally restricted Expression is in the oral epithelium at the site of incisors.
TS20: tooth Present Regionally restricted Expression is in the dental lamina of incisors.
Specimen Table 2 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: incisor dental lamina Present Regionally restricted Expression is in the gubernaculum.
TS22: molar dental lamina Present Regionally restricted Expression is in the gubernaculum of the first molar.
TS22: incisor enamel organ Present
TS22: molar enamel organ Present
TS22: incisor Present Regionally restricted Expression is in the inner dental epithelium of the incisor and first molar.
TS22: inner enamel epithelium Present Regionally restricted Expression is in the inner dental epithelium of the incisor and first molar.
TS22: molar Present Regionally restricted Expression is in the inner dental epithelium of the incisor and first molar.
Specimen Table 2 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: molar dental lamina Present Regionally restricted Expression is in the gubernaculum of the first molar.
TS24: cervical loop Present
TS24: incisor Present
TS24: inner enamel epithelium Present
TS24: molar Present
TS24: outer enamel epithelium Present
Specimen Table 2 E19.5 (newborn): postnatal newborn (more )
Note: The authors speicfy day E19.5 as the day of birth.
Structure Level Pattern Image Note
TS27: inner enamel epithelium Present First and second molar.
TS27: molar Present First and second molar.
TS27: outer enamel epithelium Present First and second molar.
TS27: enamel organ Present Regionally restricted Expression is in preameloblasts in the incisor and first molar.
TS27: cervical loop Present Regionally restricted In the second molar.
TS27: incisor dental pulp Present Regionally restricted Expression is in odontoblasts in the incisor and first molar.
TS27: molar dental pulp Present Regionally restricted Expression is in odontoblasts in the incisor and first molar.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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