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Gene Expression Data
Assay Details
Assay
Reference: J:301228 Laugel-Haushalter V, et al., From the transcription of genes involved in ectodermal dysplasias to the understanding of associated dental anomalies. Mol Syndromol. 2012 Oct;3(4):158-68
Assay type: RNA in situ
MGI Accession ID: MGI:6696296
Gene symbol: Irf6
Gene name: interferon regulatory factor 6
Probe: Irf6 probe3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral epithelium Present 2A
TS20: tooth Present Regionally restricted 2A Expression is in the dental lamina.

Specimen 2B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral epithelium Present 2B
TS20: tooth Present Regionally restricted 2B Expression is in the dental lamina.

Specimen 2C: embryonic day 14.5 (more )
Note: Cap stage incisors.
Structure Level Pattern Image Note
TS22: enamel organ Present 2C
TS22: cervical loop Strong 2C

Specimen 2D: embryonic day 14.5 (more )
Note: Cap stage first molars.
Structure Level Pattern Image Note
TS22: enamel organ Present 2D
TS22: cervical loop Strong 2D

Specimen 2E: embryonic day 16.5 (more )
Note: Bell stage lower incisor.
Structure Level Pattern Image Note
TS24: cervical loop Strong 2E
TS24: stratum intermedium Strong 2E
TS24: outer enamel epithelium Present 2E
TS24: stellate reticulum Present 2E

Specimen 2F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cervical loop Strong 2F
TS24: stratum intermedium Strong 2F
TS24: outer enamel epithelium Present 2F
TS24: stellate reticulum Present 2F

Specimen 2G: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: cervical loop Present 2G
TS27: inner enamel epithelium Present 2G
TS27: outer enamel epithelium Present 2G
TS27: stratum intermedium Present 2G
TS27: enamel organ Present Regionally restricted 2G Expression is in preameloblasts.

Specimen 2H: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: cervical loop Present 2H
TS27: inner enamel epithelium Present 2H
TS27: outer enamel epithelium Present 2H
TS27: stratum intermedium Present 2H
TS27: enamel organ Present Regionally restricted 2H Expression is in preameloblasts.

Specimen 5A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: submandibular gland epithelium Present 5A

Specimen 5F: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: vibrissa follicle Strong Regionally restricted 5F Expression is in the epithelial layer of the vibrissae follicle shafts.

Specimen Table 2 E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: oral epithelium Present Regionally restricted Expression is in the oral epithelium at the site of incisors and first molars.
TS20: tooth Present Regionally restricted Expression is in the dental lamina of incisors and first molars.

Specimen Table 2 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: incisor dental lamina Present Regionally restricted Expression is in the gubernaculum.
TS22: molar dental lamina Present Regionally restricted Expression is in the gubernaculum of the first molar.
TS22: incisor enamel organ Present
TS22: molar enamel organ Present
TS22: inner enamel epithelium Present Regionally restricted Expression is in the inner dental epithelium of the incisor and first molar.
TS22: enamel knot Present Regionally restricted Expression is in the enamel knot of the incisor and first molar.
TS22: incisor Present Regionally restricted Expression is in the enamel knot of the incisor and first molar.
TS22: molar Present Regionally restricted Expression is in the enamel knot of the incisor and first molar.

Specimen Table 2 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: incisor dental lamina Present Regionally restricted Expression is in the gubernaculum.
TS24: molar dental lamina Present Regionally restricted Expression is in the gubernaculum of the first molar.
TS24: cervical loop Present
TS24: incisor Present
TS24: inner enamel epithelium Present
TS24: molar Present
TS24: outer enamel epithelium Present
TS24: stellate reticulum Present
TS24: stratum intermedium Present

Specimen Table 2 E19.5 (newborn): postnatal newborn (more )
Note: The authors speicfy day E19.5 as the day of birth.
Structure Level Pattern Image Note
TS27: cervical loop Present Incisor, first, and second molar.
TS27: incisor Present Incisor, first, and second molar.
TS27: inner enamel epithelium Present Incisor, first, and second molar.
TS27: molar Present Incisor, first, and second molar.
TS27: outer enamel epithelium Present Incisor, first, and second molar.
TS27: stratum intermedium Present Incisor, first, and second molar.
TS27: stellate reticulum Present Second molar.
TS27: enamel organ Present Regionally restricted Expression is in preameloblasts in the incisor and first molar.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory