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Gene Expression Data
Assay Details
Assay
Reference: J:161785 Gu WX, et al., Identification of genes controlled by LMX1B in E13.5 mouse limbs. Dev Dyn. 2010 Aug;239(8):2246-55
Assay type: RNA in situ
MGI Accession ID: MGI:6695824
Gene symbol: Sim2
Gene name: single-minded family bHLH transcription factor 2
Probe: Sim2 cDNA8
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3D Fore +/+: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb mesenchyme Present Regionally restricted 3D Fore +/+ Expression is ventral-distal domain.

Specimen 3D Fore -/-: embryonic day 13.5; Lmx1btm1Rjo/Lmx1btm1Rjo (more )
Structure Level Pattern Image Note
TS21: forelimb mesenchyme Present Regionally restricted 3D Fore -/- Expression is in a ventral-distal and dorsal-distal domain.

Specimen 3D Hind +/+: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hindlimb mesenchyme Present Regionally restricted 3D Hind +/+ Expression is ventral-distal domain.

Specimen 3D Hind -/-: embryonic day 13.5; Lmx1btm1Rjo/Lmx1btm1Rjo (more )
Structure Level Pattern Image Note
TS21: hindlimb mesenchyme Present Regionally restricted 3D Hind -/- Expression is in a ventral-distal and dorsal-distal domain.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory