Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:85765
Nakajima A, et al., Expression of fibroblast growth factor receptor-3 (FGFR3), signal transducer and activator of transcription-1, and cyclin-dependent kinase inhibitor p21 during endochondral ossification: differential role of FGFR3 in skeletal development and fracture repair. Endocrinology. 2003 Oct;144(10):4659-68
|
|
Assay type:
|
RNA in situ
|
|
MGI Accession ID:
|
MGI:6695221
|
|
Gene symbol:
|
Fgfr3
|
|
Gene name:
|
fibroblast growth factor receptor 3
|
|
Probe:
|
Fgfr3 cDNA12
|
|
Probe preparation:
|
Antisense labelled with digoxigenin RNA
|
|
|
Results
|
Specimen
1A:
embryonic day 16.5
(more  )
Specimen
1A:
(close  )
|
Genetic Background:
|
C57BL/6J
|
|
Age:
|
embryonic day 16.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS24: forelimb cartilage condensation |
Strong |
Regionally restricted |
1A
,
1B
|
Expression is strong in resting and proliferating chondrocytes at the ends of the developing bones and is weak in hypertrophic chondrocytes.
|
| TS24: perichondrium |
Strong |
|
1B
,
1A
|
|
| TS24: forelimb bone |
Absent |
|
1A
|
Expression is absent in osteoblasts at the ossification center.
|
Specimen
1C:
embryonic day 19.5
(more )
Specimen
1C:
(close )
|
Genetic Background:
|
C57BL/6J
|
|
Age:
|
embryonic day 19.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS26: forelimb cartilage condensation |
Strong |
Regionally restricted |
1C
,
1D
|
Expression is strong in resting and proliferating chondrocytes at the ends of the developing bones and is weak in hypertrophic chondrocytes.
|
| TS26: perichondrium |
Strong |
|
1D
,
1C
|
Expression is stronger in the membrane surrounding the resting zone of chondrocytes.
|
| TS26: forelimb bone |
Absent |
|
1C
|
Expression is absent in osteoblasts at the ossification center.
|
|
Analysis Tools
