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Gene Expression Data
Assay Details
Assay
Reference: J:294882 Vanacker C, et al., Neuropilin-1 expression in GnRH neurons regulates prepubertal weight gain and sexual attraction. EMBO J. 2020 Aug 5;:e104633
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6695173
Gene symbol: Gnrh1
Gene name: gonadotropin releasing hormone 1
Antibody: anti-GnRH
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: The authors did not specify the antibody used, the following antibody may have been used instead: anti-GnRH (#1018) MGI:6695179.
Results
Specimen 1E control: embryonic day 14.5; Nrp1tm2Ddg/Nrp1tm2Ddg (more )
Structure Level Pattern Image Note
TS22: nerve Present Regionally restricted 1E control GnRH , 1E control Merge Expression is in migrating neurons along vomeronasal/terminal nerve fibers at the nose-brain junction.
Specimen 1E mutant: embryonic day 14.5; Nrp1tm2Ddg/Nrp1tm2Ddg, Tg(Gnrh1-cre)1Dlc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: nerve Present Regionally restricted 1E mutant Merge , 1E mutant GnRH Expression is in migrating neurons along vomeronasal/terminal nerve fibers at the nose-brain junction.
Specimen 2B Nose control: embryonic day 14.5; Nrp1tm2Ddg/Nrp1tm2Ddg (more )
Structure Level Pattern Image Note
TS22: nose Present Regionally restricted 2B control Nose Expression is in migrating neurons at the level of the nose.
Specimen 2B Nose mutant: embryonic day 14.5; Nrp1tm2Ddg/Nrp1tm2Ddg, Tg(Gnrh1-cre)1Dlc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: nose Present 2B mutant Nose
Specimen 2B OB control: embryonic day 14.5; Nrp1tm2Ddg/Nrp1tm2Ddg (more )
Structure Level Pattern Image Note
TS22: main olfactory bulb Present 2B control OB
Specimen 2B OB mutant: embryonic day 14.5; Nrp1tm2Ddg/Nrp1tm2Ddg, Tg(Gnrh1-cre)1Dlc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: main olfactory bulb Present 2B mutant OB
Specimen 2B VFB control: embryonic day 14.5; Nrp1tm2Ddg/Nrp1tm2Ddg (more )
Structure Level Pattern Image Note
TS22: forebrain Present Regionally restricted 2B control VFB
Specimen 2B VFB mutant: embryonic day 14.5; Nrp1tm2Ddg/Nrp1tm2Ddg, Tg(Gnrh1-cre)1Dlc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: forebrain Present Regionally restricted 2B mutant VFB
Specimen 2D control: postnatal; Nrp1tm2Ddg/Nrp1tm2Ddg (more )
Structure Level Pattern Image Note
TS28: accessory olfactory bulb Present 2D control
Specimen 2D mutant: postnatal; Nrp1tm2Ddg/Nrp1tm2Ddg, Tg(Gnrh1-cre)1Dlc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: accessory olfactory bulb Present 2D mutant
Specimen 2E control: postnatal; Nrp1tm2Ddg/Nrp1tm2Ddg (more )
Structure Level Pattern Image Note
TS28: medial preoptic area Present 2E control
Specimen 2E mutant: postnatal; Nrp1tm2Ddg/Nrp1tm2Ddg, Tg(Gnrh1-cre)1Dlc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: medial preoptic area Present 2E mutant
Specimen not shown E12.5 control: embryonic day 12.5; Nrp1tm2Ddg/Nrp1tm2Ddg (more )
Note: These data are summarized in table 2A.
Structure Level Pattern Image Note
TS20: brain Present
Specimen not shown E12.5 mutant: embryonic day 12.5; Nrp1tm2Ddg/Nrp1tm2Ddg, Tg(Gnrh1-cre)1Dlc/0 (more )
Note: Conditional mutant. These data are summarized in table 2A.
Structure Level Pattern Image Note
TS20: brain Present
Specimen not shown E18.5 control: embryonic day 18.5; Nrp1tm2Ddg/Nrp1tm2Ddg (more )
Note: These data are summarized in table 2A.
Structure Level Pattern Image Note
TS26: brain Present
Specimen not shown E18.5 mutant: embryonic day 18.5; Nrp1tm2Ddg/Nrp1tm2Ddg, Tg(Gnrh1-cre)1Dlc/0 (more )
Note: Conditional mutant. These data are summarized in table 2A.
Structure Level Pattern Image Note
TS26: brain Present
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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