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Gene Expression Data
Assay Details
Assay
Reference: J:294646 Stupnikov MR, et al., Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. Elife. 2019 Oct 21;8:e50487
Assay type: RNA in situ
MGI Accession ID: MGI:6695096
Gene symbol: Jag1
Gene name: jagged 1
Probe: Jag1 probe14
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: bronchus epithelium Absent 1C
TS20: trachea epithelium Absent 1C
TS20: lung vascular element Strong 1C
Specimen 1D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: bronchus epithelium Absent 1D Jag1 left , 1D Jag1 right
TS21: trachea epithelium Absent 1D Jag1 left , 1D Jag1 right
TS21: lung vascular element Strong 1D Jag1 right , 1D Jag1 left
Specimen 2D: embryonic day 18.5; Jag2tm2.1Grid/Jag2tm2.1Grid, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 2D
TS26: lung vascular element Present 2D
Specimen 1-S1B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung vascular element Strong 1 S1B lower right , 1 S1B lower left , 1 S1B upper
TS22: bronchus epithelium Trace 1 S1B lower left , 1 S1B lower right , 1 S1B upper Nearly background signals.
TS22: trachea epithelium Trace 1 S1B lower left , 1 S1B lower right , 1 S1B upper Nearly background signals.
Specimen 1-S1D: embryonic day 15.5 (more )
Note: Double labeled: blue - Jag1; brown - Foxj1 (assay MGI:6695202).
Structure Level Pattern Image Note
TS23: main bronchus epithelium Weak 1 S1D upper left
TS23: bronchiole epithelium Present 1 S1D upper right , 1 S1D lower left , 1 S1D lower right Preferentially in multiciliated cells.
TS23: lung vascular element Strong 1 S1D upper right , 1 S1D lower left
Specimen 1-S1F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: bronchiole epithelium Strong 1 S1F
TS26: lung vascular element Strong 1 S1F
Specimen not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: respiratory system epithelium Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory