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Gene Expression Data
Assay Details
Assay
Reference: J:294646 Stupnikov MR, et al., Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. Elife. 2019 Oct 21;8:e50487
Assay type: RNA in situ
MGI Accession ID: MGI:6695093
Gene symbol: Jag2
Gene name: jagged 2
Probe: Jag2 probe8
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A left: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: trachea epithelium Present 1A left

Specimen 1A right: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: bronchus epithelium Absent 1A right

Specimen 1B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: bronchus epithelium Weak Regionally restricted 1B left , 1B right Expressed in the epithelium of extrapulmonary but not intrapulmonary airways.
TS20: lung vascular element Strong 1B left , 1B right
TS20: esophagus epithelium Strong 1B left

Specimen 1D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: trachea epithelium Present 1D Jag2 left , 1D Jag2 right
TS21: bronchus epithelium Present Regionally restricted 1D Jag2 right , 1D Jag2 left Expressed in extrapulmonary bronchi.

Specimen 1-S1A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung vascular element Present 1 S1A lower left , 1 S1A upper
TS22: trachea epithelium Present 1 S1A lower left , 1 S1A upper
TS22: bronchus epithelium Present 1 S1A lower right , 1 S1A upper

Specimen 1-S1C E15.5: embryonic day 15.5 (more )
Note: Double labeled: blue - Jag2; brown - Trp63 (assay MGI:6695203).
Structure Level Pattern Image Note
TS23: trachea epithelium Present 1 S1C upper left , 1 S1C upper right Expressed in tracheal epithelium enriched in basal cell progenitors.

Specimen 1-S1C E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: trachea epithelium Present 1 S1C lower Expressed in tracheal epithelium enriched in basal cell progenitors.

Specimen 1-S1E: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: main bronchus epithelium Present 1 S1E inset
TS26: lung vascular element Present 1 S1E
TS26: lobar bronchus epithelium Trace 1 S1E Nearly absent in intrapulmonary airways.

Specimen 1-S2A/B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: main bronchus epithelium Present Regionally restricted 1 S2B left upper , 1 S2A left , 1 S2B right upper Expressed in proximal but not in more distal main bronchus.
TS22: lung vascular element Strong 1 S2B right upper , 1 S2A left

Specimen not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: respiratory system epithelium Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory