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Gene Expression Data
Assay Details
Assay
Reference: J:93609 Fuccillo M, et al., Temporal requirement for hedgehog signaling in ventral telencephalic patterning. Development. 2004 Oct;131(20):5031-40
Assay type: RNA in situ
MGI Accession ID: MGI:6693511
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Probe: Nkx2-1 cDNA5
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3E: embryonic day 10.0; Smotm1Amc/Smotm2Amc (more )
Structure Level Pattern Image Note
TS16: telencephalon Present Regionally restricted 3E Expressed in the ventral region, forming a boundary with the Pax6-positive cortical primordium.
Specimen 3F: embryonic day 10.0; Foxg1tm1(cre)Skm/Foxg1+, Smotm1Amc/Smotm2Amc (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS16: telencephalon Present Regionally restricted 3F The wild-type ventral expression was absent from the mutant, with the exception of a small region of staining that is of diencephalic origin.
Specimen 4G: embryonic day 12.5; Smotm1Amc/Smotm2Amc (more )
Structure Level Pattern Image Note
TS20: medial ganglionic eminence Present Widespread 4G
TS20: caudal ganglionic eminence Present Regionally restricted 4G Expressed in the anterior-most domain.
Specimen 4H: embryonic day 12.5; Foxg1tm1(cre)Skm/Foxg1+, Smotm1Amc/Smotm2Amc (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: diencephalon Present 4H
Specimen S1E: embryonic day 9.0; Smotm1Amc/Smotm2Amc (more )
Note: 14-17 somites
Structure Level Pattern Image Note
TS14: future telencephalon Present Regionally restricted S1E Expressed in the ventral region, forming a boundary with the Pax6-positive cortical primordium.
Specimen S1F: embryonic day 9.0; Foxg1tm1(cre)Skm/Foxg1+, Smotm1Amc/Smotm2Amc (more )
Note: Conditional mutant. 14-17 somites
Structure Level Pattern Image Note
TS14: future telencephalon Absent S1F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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