About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:121266 Yang DH, et al., Disabled-2 is an epithelial surface positioning gene. J Biol Chem. 2007 Apr 27;282(17):13114-22
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6693297
Gene symbol: Lrp2
Gene name: low density lipoprotein receptor-related protein 2
Antibody: anti-megalin
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 2B +/+ or +/-: embryonic day 5.5; Dab2tm1Xxx/Dab2+ (more )
Note: This specimen is is either +/+ or +/-. Double labeled: green - Lrp2; red - Dab2 (assay MGI:6693298).
Structure Level Pattern Image Note
TS8: extraembryonic visceral endoderm Present 2B Dab2 WT Expression is at the apical edge of visceral endoderm cells.
Specimen 2B +/+: embryonic day 5.5 (more )
Note: Double labeled: green - Lrp2; red - Dab2 (assay MGI:6693298).
Structure Level Pattern Image Note
TS8: extraembryonic visceral endoderm Present Expression is at the apical edge of visceral endoderm cells.
Specimen 2B-/-: embryonic day 5.5; Dab2tm1Xxx/Dab2tm1Xxx (more )
Note: Double labeled: green - Lrp2; red - Dab2 (assay MGI:6693298).
Structure Level Pattern Image Note
TS8: embryo Present Regionally restricted 2B Dab2-/- Expression is in presumptive visceral endoderm cells located in the interior of the embryonic cell mass.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory