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Gene Expression Data
Assay Details
Assay
Reference: J:102464 Lee NV, et al., Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1. J Biol Chem. 2005 Oct 14;280(41):34796-804
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6690602
Gene symbol: Acan
Gene name: aggrecan
Antibody: neo-epitope TASELE antibody
Detection system: Secondary antibody coupled to fluorescein
Assay notes: The antibody used recognizes the cleaved form of the protein.
Results
Specimen 7Dg: embryonic day 15.5 (more )
Note: Double labeled: green - Acan; red - Adamts1 (assay MGI:6690599).
Structure Level Pattern Image Note
TS23: basement membrane Present Regionally restricted 7Di , 7Dg Expression is in the apical epithelial tubules and the basement membrane.
TS23: renal tubule Present Regionally restricted 7Di , 7Dg Expression is in the apical epithelial tubules and the basement membrane.
Specimen 7Dj: embryonic day 15.5; Adamts1tm1Mlia/Adamts1tm1Mlia (more )
Note: Double labeled: green - Acan; red - Adamts1 (assay MGI:6690599).
Structure Level Pattern Image Note
TS23: basement membrane Weak Regionally restricted 7Dl , 7Dj Expression is in the apical epithelial tubules and the basement membrane.
TS23: renal tubule Weak Regionally restricted 7Dl , 7Dj Expression is in the apical epithelial tubules and the basement membrane.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory