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Gene Expression Data
Assay Details
Assay
Reference: J:102464 Lee NV, et al., Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1. J Biol Chem. 2005 Oct 14;280(41):34796-804
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6690599
Gene symbol: Adamts1
Gene name: ADAM metallopeptidase with thrombospondin type 1 motif 1
Antibody: ADAMTS-1 GP12 antibody
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 4B WT: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: basement membrane Present Patchy 4B Wild-type Expression is in the apical epithelial tubules and the basement membrane.
TS23: renal tubule Present Patchy 4B Wild-type Expression is in the apical epithelial tubules and the basement membrane.
Specimen 4B KO: embryonic day 15.5; Adamts1tm1Mlia/Adamts1tm1Mlia (more )
Structure Level Pattern Image Note
TS23: metanephros Absent 4B KO
Specimen 4Cb: embryonic day 15.5 (more )
Note: Double labeled: red - Adamts1; green - Fbln1 (assay MGI:6690592).
Structure Level Pattern Image Note
TS23: basement membrane Present Patchy 4Cc , 4Cb Expression is in the basement membrane of the developing nephron.
TS23: early nephron Present Patchy 4Cc , 4Cb Expression is in the basement membrane of the developing nephron.
Specimen 4Ce: embryonic day 15.5 (more )
Note: Double labeled: red - Adamts1; green - Fbln1 (assay MGI:6690592).
Structure Level Pattern Image Note
TS23: basement membrane Present Patchy 4Cf , 4Ce Expression is in the basement membrane of the developing nephron.
TS23: early nephron Present Patchy 4Cf , 4Ce Expression is in the basement membrane of the developing nephron.
Specimen 4Ch: embryonic day 15.5 (more )
Note: Double labeled: red - Adamts1; green - Fbln1 (assay MGI:6690592).
Structure Level Pattern Image Note
TS23: basement membrane Present Patchy 4Ch , 4Ci Expression is in the basement membrane of the developing nephron.
TS23: early nephron Present Patchy 4Ch , 4Ci Expression is in the basement membrane of the developing nephron.
Specimen 7Db: embryonic day 15.5 (more )
Note: Double labeled: red - Adamts1; green - Acan (assay MGI:6690601).
Structure Level Pattern Image Note
TS23: basement membrane Present Regionally restricted 7Dc , 7Db Expression is in the apical epithelial tubules and the basement membrane.
TS23: renal tubule Present Regionally restricted 7Dc , 7Db Expression is in the apical epithelial tubules and the basement membrane.
Specimen 7De: embryonic day 15.5; Adamts1tm1Mlia/Adamts1tm1Mlia (more )
Note: Double labeled: red - Adamts1; green - Acan (assay MGI:6690601).
Structure Level Pattern Image Note
TS23: metanephros Absent 7De , 7Df
Specimen 7Dh: embryonic day 15.5 (more )
Note: Double labeled: red - Adamts1; green - Acan (assay MGI:6690602).
Structure Level Pattern Image Note
TS23: basement membrane Present Regionally restricted 7Di , 7Dh Expression is in the apical epithelial tubules and the basement membrane.
TS23: renal tubule Present Regionally restricted 7Di , 7Dh Expression is in the apical epithelial tubules and the basement membrane.
Specimen 7Dk: embryonic day 15.5; Adamts1tm1Mlia/Adamts1tm1Mlia (more )
Note: Double labeled: red - Adamts1; green - Acan (assay MGI:6690602).
Structure Level Pattern Image Note
TS23: metanephros Absent 7Dl , 7Dk
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory