Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Ccr2em3(dre/ERT2)Smoc
Name:	C-C motif chemokine receptor 2; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
MGI ID:	MGI:6682024
Synonyms:	CCR2-2A-DreER, Ccr2em3(2A-DreERT2)Smoc
Gene:	Ccr2  Location: Chr9:123901987-123913594 bp, + strand  Genetic Position: Chr9, 75.05 cM, cytoband F
Alliance:	Ccr2em3(dre/ERT2)Smoc page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Ccr2em3(dre/ERT2)Smoc expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Ccr2 (MGI:106185)   Mutation details: A 2A-DreERT2 expression cassette was knocked into the Ccr2 gene stop codon site via CRISPR/Cas9 mediated recombination. (J:238766, J:304636)

Activity:	Tissue activity of this recombinase allele
Driver:	Ccr2 (mouse) Summary of all recombinase alleles driven by Ccr2. Alliance mouse Ccr2 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccr2 Mutation:	40 strains or lines available

Original:	J:304636 Han X, et al., A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting. Cell Stem Cell. 2021 Feb 2;
All:	2 reference(s)