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Gene Expression Data
Assay Details
Assay
Reference: J:186516 Baron O, et al., Cooperation of nuclear fibroblast growth factor receptor 1 and Nurr1 offers new interactive mechanism in postmitotic development of mesencephalic dopaminergic neurons. J Biol Chem. 2012 Jun 8;287(24):19827-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6681921
Gene symbol: Nr4a2
Gene name: nuclear receptor subfamily 4, group A, member 2
Antibody: anti-Nurr1 (N-20): sc-991
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1A/B/C/D: embryonic day 14.5 (more )
Note: Ventral midbrain. Double labeled: green - Nr4a2; red - Th (assay MGI:6681923).
Structure Level Pattern Image Note
TS22: brain subventricular zone Present Regionally restricted 1B , 1A Expressed in the postmitotic dopaminergic precursors of subventricular zone.
TS22: midbrain ventricular layer Absent 1A , 1B
TS22: midbrain mantle layer Present 1C , 1B , 1A , 1D Coexpressed with Th in the dopaminergic neurons.
Specimen 1E/F/G/H: embryonic day 14.5; Fgf2tm1Zllr/Fgf2tm1Zllr (more )
Note: Ventral midbrain. Double labeled: green - Nr4a2; red - Th (assay MGI:6681923).
Structure Level Pattern Image Note
TS22: brain subventricular zone Present Regionally restricted 1F , 1E Similar as in the wild-type, expressed in the postmitotic dopaminergic precursors of subventricular zone.
TS22: midbrain mantle layer Present 1E , 1F , 1G , 1H Similar as in the wild-type, coexpressed with Th in the dopaminergic neurons.
TS22: midbrain ventricular layer Absent 1E , 1F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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